货号 (SKU)

包装规格

是否现货

价格

数量

Ab006467-10μg

10μg

现货

Ab006467-50μg

50μg

现货

Ab006467-100μg

100μg

现货

Ab006467-1mg

1mg

期货

基本信息

产品名称	CD2 Mouse mAb
别名	CD2小鼠单克隆抗体 \| CD2小鼠单抗
英文别名	Erythrocyte receptor \| LFA-2 \| LFA-3 receptor \| Rosette receptor \| T-cell surface antigen T11/Leu-5
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	小鼠(Mouse)
特异性	CD2
种属反应性	人(Human)
免疫原	Human phytohemagglutinin-treated lymphoblasts
阳性对照	Flow: Human peripheral blood lymphocytes.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	RPA-2.10
Format	Whole IgG
亚型	Mouse IgG1
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, pH 7.2-7.4
防腐剂	No
浓度	见COA
储存温度	2-8°C储存
运输条件	冰袋运输
稳定性与储存	4°C 下运输。4°C 长期保存（12 个月）。收货后建议分装。
分子类型	抗体

关联靶点（人）

CD2 Tclin T细胞表面抗原CD2(T-cell surface antigen CD2) (0 活性数据)

点击查看靶蛋白信息： CD2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

CD2 Tclin T-cell surface antigen CD2 (9 活性数据)

点击查看靶蛋白信息： CD2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: CD2 Mouse mAb (Ab006467)

CD2 Mouse mAb (Ab006467) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD2 with CD2 Mouse mAb (Ab006467) at 0.1 μg/mL (right panel) compared with mouse IgG (Ab170221) - Isotype Control (left panel). Goat anti-Mouse IgG H&L (FITC) (Ab156254) at a dilution of 1/1000 was used as the secondary antibody.

Flow Cytometry: CD2 Mouse mAb (Ab006467)

CD2 Mouse mAb (Ab006467) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD2 (red) with CD2 Mouse mAb (Ab006467) at 0.1 μg/mL for 1 hour at 4°C. Goat anti-Mouse IgG H&L (FITC) (Ab156254) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	1μg/100w cells

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0102386	分析证书	Ab006467
ZJ24F0102387	分析证书	Ab006467
ZJ24F0102388	分析证书	Ab006467

技术文档和文章

利用甲醇通透法进行流式细胞术

Categories: 实验方案（Protocols）

探索主题:

流式细胞术流式抗体流式实验甲醇通透细胞分选细胞分型免疫研究细胞内抗原检测

Flow Cytometry Using Methanol Permeabilization

Categories: 实验方案（Protocols）

探索主题:

Flow Cytometry FlowCytometry methanolpermeabilization flowcytometryantibodies Cell Sorting Cell Typing Immunology Research Intracellular Antigen Detection

Flow Cytometry Using Methanol Permeabilization

Categories: 实验方案（Protocols）

探索主题:

Flow Cytometry FlowCytometry methanolpermeabilization flowcytometryantibodies Cell Sorting Cell Typing Immunology Research Intracellular Antigen Detection

可替换产品

引用文献

1. da Silva AJ, Brickelmaier M, Majeau GR, Li Z, Su L, Hsu YM, Hochman PS. (2002) Alefacept, an immunomodulatory recombinant LFA-3/IgG1 fusion protein, induces CD16 signaling and CD2/CD16-dependent apoptosis of CD2(+) cells.. J Immunol, 168 (9): (4462-71). [PMID:11970990]
2. Giddu S, Subramanian V, Yoon HS, Satyanarayanajois SD.. (2009) Design of beta-hairpin peptides for modulation of cell adhesion by beta-turn constraint.. J Med Chem, 52 (3): (726-736). [PMID:19123855] [10.1021/jm8008212]
3. Gokhale A, Weldeghiorghis TK, Taneja V, Satyanarayanajois SD.. (2011) Conformationally constrained peptides from CD2 to modulate protein-protein interactions between CD2 and CD58.. J Med Chem, 54 (15): (5307-5319). [PMID:21755948] [10.1021/jm200004e]
4. Hahn, W C WC, Menu, E E, Bothwell, A L AL, Sims, P J PJ and Bierer, B E BE.. (1992) Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.. Science (New York, N.Y.), (26): [PMID:1377404]
5. Seed, B B and Aruffo, A A.. (1987) Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2437578]
6. Peterson, A A and Seed, B B.. (1987) Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2).. Nature, [PMID:2444890]
7. Sayre, P H PH and 7 more authors.. (1987) Molecular cloning and expression of T11 cDNAs reveal a receptor-like structure on human T lymphocytes.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2883656]
8. Diamond, D J DJ, Clayton, L K LK, Sayre, P H PH and Reinherz, E L EL.. (1988) Exon-intron organization and sequence comparison of human and murine T11 (CD2) genes.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2894031]
9. Lang, G G and 7 more authors.. (1988) The structure of the human CD2 gene and its expression in transgenic mice.. The EMBO journal, [PMID:2901953]
10. Sewell, W A WA, Brown, M H MH, Dunne, J J, Owen, M J MJ and Crumpton, M J MJ.. (1986) Molecular cloning of the human T-lymphocyte surface CD2 (T11) antigen.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3490670]
11. Wyss, D F DF and 8 more authors.. (1995) Conformation and function of the N-linked glycan in the adhesion domain of human CD2.. Science (New York, N.Y.), (1): [PMID:7544493]
12. Withka, J M JM and 5 more authors.. (1993) Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2.. Structure (London, England : 1993), (15): [PMID:7915183]
13. Bodian, D L DL, Jones, E Y EY, Harlos, K K, Stuart, D I DI and Davis, S J SJ.. (1994) Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.. Structure (London, England : 1993), (15): [PMID:7994575]
14. Li, J J and 7 more authors.. (1998) A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.. The EMBO journal, (15): [PMID:9857189]
15. Wang, J H JH and 7 more authors.. (1999) Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.. Cell, (11): [PMID:10380930]
16. Chen, X X, Ji, Z L ZL and Chen, Y Z YZ.. (2002) TTD: Therapeutic Target Database.. Nucleic acids research, (1): [PMID:11752352]
17. and Ortonne, J-P JP.. (2003) Clinical response to alefacept: results of a phase 3 study of intramuscular administration of alefacept in patients with chronic plaque psoriasis.. Journal of the European Academy of Dermatology and Venereology : JEADV, [PMID:12795770]
18. Goedkoop, Amber Y AY and 8 more authors.. (2004) Alefacept therapy reduces the effector T-cell population in lesional psoriatic epidermis.. Archives of dermatological research, [PMID:14968366]
19. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414]
20. Sjöblom, Tobias T and 28 more authors.. (2006) The consensus coding sequences of human breast and colorectal cancers.. Science (New York, N.Y.), (13): [PMID:16959974]
21. Larsen, R R, Ryder, L P LP, Svejgaard, A A and Gniadecki, R R.. (2007) Changes in circulating lymphocyte subpopulations following administration of the leucocyte function-associated antigen-3 (LFA-3)/IgG1 fusion protein alefacept.. Clinical and experimental immunology, [PMID:17403057]
22. Chamian, Francesca F and 11 more authors.. (2007) Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis.. Journal of translational medicine, (7): [PMID:17555598]
23. Grier, Jennifer T JT and 8 more authors.. (2012) Human immunodeficiency-causing mutation defines CD16 in spontaneous NK cell cytotoxicity.. The Journal of clinical investigation, [PMID:23006327]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

CD2 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

CD2 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器