货号 (SKU)

包装规格

是否现货

价格

数量

Ab005506-10μg

10μg

现货

Ab005506-50μg

50μg

现货

Ab005506-100μg

100μg

现货

Ab005506-1mg

1mg

期货

基本信息

产品名称	SHBG Mouse mAb
别名	SHBG小鼠单克隆抗体 \| SHBG小鼠单抗
英文别名	ABP \| SBP \| Sex steroid-binding protein \| SHBG \| TeBG \| Testis-specific androgen-binding protein \| Testosterone-estradiol-binding globulin \| Testosterone-estrogen-binding globulin
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	小鼠(Mouse)
特异性	SHBG
种属反应性	人(Human)
免疫原	Recombinant Human SHBG protein
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	3D8-2
Format	Whole IgG
亚型	Mouse IgG1
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Affinity chromatography
配对抗体	[Ab005514] Monoclonal Human SHBG Antibody as Capture antibody in ELISA, CLIA, LF, GICA, FIA
物理外观	Liquid
储存缓冲液	10mM PBS, pH7.4
防腐剂	No
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at 2-8°C short term (30 days). Store at -20°C long term (36 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
分子类型	抗体

关联靶点（人）

SHBG Tchem 性激素结合球蛋白(Sex hormone-binding globulin) (0 活性数据)

点击查看靶蛋白信息： SHBG

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Sandwich ELISA - SHBG Mouse mAb Pair (Ab005514 & Ab005506)

Sandwich ELISA - SHBG protein standard curve
SHBG protein was serially diluted 4-fold and captured by SHBG Mouse mAb (Ab005514) coated on a Clear Polystyrene Microplate (W291037). SHBG Mouse mAb (Ab005506) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (np156148).

Relevance of detection results between aladdin Antibody Pair (Ab005514 & Ab005506) and Beckman Coulter in CLIA

Relevance of detection results between aladdin Antibody Pair (Ab005514 & Ab005506) and Beckman Coulter in CLIA
·Capture antibody: SHBG Mouse mAb (Ab005514)
·Detection antibody: SHBG Mouse mAb (Ab005506)

Binding ELISA - SHBG Mouse mAb (Ab005506)

Binding ELISA - SHBG Mouse mAb (Ab005506)
Immobilized Recombinant Human SHBG Protein at 2.0 μg/mL can bind SHBG Mouse mAb (Ab005506) with the EC₅₀ of 5.33 ng/mL.

应用

应用名称	稀释比例
FIA	1 mg/mL
CLIA	100μg/4μg AE

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F1011872	分析证书	Ab005506
ZJ23F1001306	分析证书	Ab005506
ZJ23F1001307	分析证书	Ab005506

可替换产品

引用文献

1. Liu A, Carlson KE, Katzenellenbogen JA.. (1992) Synthesis of high affinity fluorine-substituted ligands for the androgen receptor. Potential agents for imaging prostatic cancer by positron emission tomography.. J Med Chem, 35 (11): (2113-2129). [PMID:1597861] [10.1021/jm00089a024]
2. Choe YS, Lidström PJ, Chi DY, Bonasera TA, Welch MJ, Katzenellenbogen JA.. (1995) Synthesis of 11 beta-[18F]fluoro-5 alpha-dihydrotestosterone and 11 beta-[18F]fluoro-19-nor-5 alpha-dihydrotestosterone: preparation via halofluorination-reduction, receptor binding, and tissue distribution.. J Med Chem, 38 (5): (816-825). [PMID:7877147] [10.1021/jm00005a009]
3. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P et al.. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res, 14 (10B): (2121-7). [PMID:15489334]
4. Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K et al.. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs.. Nat Genet, 36 (1): (40-5). [PMID:14702039]
5. Kortylewicz ZP, Nearman J, Baranowska-Kortylewicz J.. (2009) Radiolabeled 5-iodo-3'-O-(17beta-succinyl-5alpha-androstan-3-one)-2'-deoxyuridine and its 5'-monophosphate for imaging and therapy of androgen receptor-positive cancers: synthesis and biological evaluation.. J Med Chem, 52 (16): (5124-5143). [PMID:19653647] [10.1021/jm9005803]
6. Power, S G SG and 5 more authors.. (1992) Molecular analyses of a human sex hormone-binding globulin variant: evidence for an additional carbohydrate chain.. The Journal of clinical endocrinology and metabolism, [PMID:1400872]
7. Gershagen, S S, Lundwall, A A and Fernlund, P P.. (1989) Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis.. Nucleic acids research, (25): [PMID:2587256]
8. Hammond, G L GL, Underhill, D A DA, Rykse, H M HM and Smith, C L CL.. (1989) The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs.. Molecular endocrinology (Baltimore, Md.), [PMID:2608061]
9. Que, B G BG and Petra, P H PH.. (1987) Characterization of a cDNA coding for sex steroid-binding protein of human plasma.. FEBS letters, (27): [PMID:2956125]
10. Gershagen, S S, Fernlund, P P and Lundwall, A A.. (1987) A cDNA coding for human sex hormone binding globulin. Homology to vitamin K-dependent protein S.. FEBS letters, (10): [PMID:2956126]
11. Walsh, K A KA and 5 more authors.. (1986) Amino acid sequence of the sex steroid binding protein of human blood plasma.. Biochemistry, (18): [PMID:3542030]
12. Hammond, G L GL and 7 more authors.. (1987) The cDNA-deduced primary structure of human sex hormone-binding globulin and location of its steroid-binding domain.. FEBS letters, (4): [PMID:3569533]
13. Hammond, G L GL, Robinson, P A PA, Sugino, H H, Ward, D N DN and Finne, J J.. (1986) Physicochemical characteristics of human sex hormone binding globulin: evidence for two identical subunits.. Journal of steroid biochemistry, [PMID:3702459]
14. Hardy, D O DO, Cariño, C C, Catterall, J F JF and Larrea, F F.. (1995) Molecular characterization of a genetic variant of the steroid hormone-binding globulin gene in heterozygous subjects.. The Journal of clinical endocrinology and metabolism, [PMID:7714097]
15. Cargill, M M and 17 more authors.. (1999) Characterization of single-nucleotide polymorphisms in coding regions of human genes.. Nature genetics, [PMID:10391209]
16. Grishkovskaya, I I and 5 more authors.. (2000) Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.. The EMBO journal, (15): [PMID:10675319]
17. Hammond, G L GL, Rabe, T T and Wagner, J D JD.. (2001) Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy.. American journal of obstetrics and gynecology, [PMID:11521119]
18. Grishkovskaya, Irina I, Avvakumov, George V GV, Hammond, Geoffrey L GL, Catalano, Maria G MG and Muller, Yves A YA.. (2002) Steroid ligands bind human sex hormone-binding globulin in specific orientations and produce distinct changes in protein conformation.. The Journal of biological chemistry, (30): [PMID:12065592]
19. Jin, Pei P and 7 more authors.. (2004) PCR isolation and cloning of novel splice variant mRNAs from known drug target genes.. Genomics, [PMID:15028279]
20. Liu, Tao T and 6 more authors.. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.. Journal of proteome research, [PMID:16335952]
21. Zody, Michael C MC and 73 more authors.. (2006) DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.. Nature, (20): [PMID:16625196]
22. Radin, Daniel P DP and Patel, Parth P.. (2016) Delineating the molecular mechanisms of tamoxifen's oncolytic actions in estrogen receptor-negative cancers.. European journal of pharmacology, (15): [PMID:27083550]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

SHBG Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

SHBG Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

相关产品

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器