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Tau Antibody - Primary antibody, specific to MAPT, Rabbit IgG

COA COA
    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Pig,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab130337
Grouped product items
SKU Size
Availability
 Price Qty
Ab130337-10μl
10μl
10
$59.90
Ab130337-50μl
50μl
4
$169.90
Ab130337-100μl
100μl
2
$269.90
Ab130337-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

pAb; Rabbit anti Human Tau Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: MAPT
Accession#:P10636 (7) Gene ID:4137 (7)

Basic Description

Product Name Tau Antibody - Primary antibody, specific to MAPT, Rabbit IgG
Synonyms Neurofibrillary tangle protein | Paired helical filament-tau | PHF-tau | AI413597 antibody | AW045860 antibody | DDPAC antibody | FLJ31424 antibody | FTDP 17 antibody | G protein beta1/gamma2 subunit interacting factor 1 antibody | MAPT antibody | MAPTL a
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, High Performance, See COA
Host species Rabbit
Specificity MAPT
Immunogen Recombinant MAPT expressed in E.coli (AA 130-386)
Positive Control WB: HeLa, SK-N-SH and C6 cell lysates. IHC: Human breast cancer, glioma, lung cancerl tissues.
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, High Performance, Validated
Product Description

Rabbit anti Human Tau Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 0.01-3µg/mL
IHC: 5-20µg/mL
Protein Function
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified + Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

MAPT Tclin Microtubule-associated protein tau (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
MAPT Tclin Microtubule-associated protein tau (95507 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAPT Tclin KEAP1/Microtubule-associated protein tau (1 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAPT Tclin KEAP1/Cullin-3/Microtubule-associated protein tau (13 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Tau Antibody (Ab130337) - Western Blot
All lanes: Tau Antibody (Ab130337) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 79 kDa
Observed band size: 33, 66 kDa
Exposure time: 200.0 s

Tau Antibody (Ab130337) - IHC
DAB staining on IHC
Samples: Human Breast cancer Tissue
Primary Ab: 10 µg/mL Tau Antibody (Ab130337) 
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Tau Antibody (Ab130337) - IHC
DAB staining on IHC
Samples: Human Glioma Tissue
Primary Ab: 10 µg/mL Tau Antibody (Ab130337)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Tau Antibody (Ab130337) - IHC
DAB staining on IHC
Samples: Human Lung cancer Tissue
Primary Ab: 10 µg/mL Tau Antibody (Ab130337)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Tau Antibody (Ab130337) - IHC
DAB staining on IHC
Sample: Human Glioma Tissue
Primary Ab: 10 µg/mL Tau Antibody (Ab130337)
Control: Used PBS instead of primary antibody
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.

Application

Application Dilution info
WB

0.01-3 µg/mL
IHC

5-20 µg/mL

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0505955 Certificate of Analysis May 22, 2024 Ab130337
ZJ24F0505956 Certificate of Analysis May 22, 2024 Ab130337
ZJ24F0505957 Certificate of Analysis May 22, 2024 Ab130337

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