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Recombinant PODXL Antibody - Primary antibody, specific to PODXL, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab122517
Grouped product items
SKU Size
Availability
Price Qty
Ab122517-10μl
10μl
1
$66.90
Ab122517-50μl
50μl
1
$189.90
Ab122517-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab122517-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,809.90

Recombinant; Rabbit anti Human PODXL Antibody; WB; Unconjugated

Basic Description

Product Name Recombinant PODXL Antibody - Primary antibody, specific to PODXL, Rabbit IgG
Synonyms GCTM-2 antigen antibody | Gp2 antibody | Gp200 antibody | MGC138240 antibody | PC antibody | PCLP antibody | PCLP-1 antibody | PCLP1 antibody | Pcx antibody | Podocalyxin antibody | Podocalyxin like antibody | Podocalyxin like protein antibody | Podocalyx
Specifications & Purity ExactAb™, Validated, Recombinant, 0.6 mg/mL
Host species Rabbit
Specificity PODXL
Immunogen A synthetic peptide derived from human PODXL (AA 300-479).
Positive Control WB: HEK293, Raji, HeLa and HT-29 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human PODXL Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.6 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PODXL Tbio Podocalyxin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
UBQLN1 Tbio Ubiquilin-1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant PODXL Antibody (Ab122517) - Western Blot
All lanes: Recombinant PODXL Antibody (Ab122517) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/50000 dilution

Predicted band size: 59 kDa
Observed band size: 164,183 kDa
Exposure time: 76.5 s

Recombinant PODXL Antibody (Ab122517) - Western Blot
All lanes: Recombinant PODXL Antibody (Ab122517) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 59 kDa
Observed band size: 164, 183 kDa
Exposure time: 28.3 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0302993 Certificate of Analysis Mar 04, 2024 Ab122517
ZJ24F0302992 Certificate of Analysis Mar 04, 2024 Ab122517

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