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Recombinant PIWIL1 Antibody - Primary antibody, specific to PIWIL1, Rabbit IgG

COA COA
    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab121977
Grouped product items
SKU Size
Availability
 Price Qty
Ab121977-10μl
10μl
2
$59.90
Ab121977-50μl
50μl
1
$169.90
Ab121977-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$279.90
Ab121977-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human PIWIL1 Antibody; WB; Unconjugated

View related series
Click to view target information: PIWIL1
Accession#:Q96J94 (1) Gene ID:9271 (1) PIWIL1 (1)

Basic Description

Product Name Recombinant PIWIL1 Antibody - Primary antibody, specific to PIWIL1, Rabbit IgG
Synonyms EC 3.1.26.- | CT80.1 | HIWI | HIWIpiwi homolog | MIWI | piwi (Drosophila)-like 1 | PIWI | PIWIL1 | piwi-like 1 (Drosophila) | piwi-like protein 1 | HIWI antibody | MIWI antibody | Piwi (Drosophila) like 1 antibody | PIWI antibody | Piwi homolog antibody |
Specifications & Purity ExactAb™, Validated, Recombinant, 2.5 mg/mL
Host species Rabbit
Specificity PIWIL1
Immunogen A synthetic peptide derived from human PIWIL1 (AA 754-800)
Positive Control WB: Hep G2, Jurkat, HeLa and C6 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human PIWIL1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability (By similarity). Isoform 3 may be a negative developmental regulator.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 2.5 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PIWIL1 Tbio Piwi-like protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant PIWIL1 Antibody (Ab121977) - Western Blot
All lanes: Recombinant PIWIL1 Antibody (Ab121977) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 99 kDa
Observed band size: 98, 103 kDa
Exposure time: 9.6 s 

Recombinant PIWIL1 Antibody (Ab121977) - Western Blot
All lanes: Recombinant PIWIL1 Antibody (Ab121977) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 99 kDa
Observed band size: 109 kDa
Exposure time: 10.4 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0405029 Certificate of Analysis Apr 29, 2024 Ab121977
ZJ24F0405028 Certificate of Analysis Apr 29, 2024 Ab121977

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