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Recombinant ICOS Antibody - Primary antibody, specific to ICOS, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab109267
Grouped product items
SKU Size
Availability
Price Qty
Ab109267-10μl
10μl
2
$79.90
Ab109267-50μl
50μl
1
$249.90
Ab109267-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
Ab109267-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Recombinant; Rabbit anti Human ICOS Antibody; WB; Unconjugated

Basic Description

Product Name Recombinant ICOS Antibody - Primary antibody, specific to ICOS, Rabbit IgG
Synonyms Inducible T cell co stimulator antibody | Inducible T-cell costimulator antibody | MGC39850 antibody | AILIM | CD278 | CVID1 | Activation inducible lymphocyte immunomediatory molecule antibody | Activation-inducible lymphocyte immunomediatory molecule ant
Specifications & Purity ExactAb™, Validated, Recombinant, 3.0 mg/mL
Host species Rabbit
Specificity ICOS
Immunogen A synthetic peptide derived from human ICOS (AA 40-95)
Positive Control WB: Jurkat lysate.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human ICOS Antibody, Recombinant, could be used for WB and so on.
Application
· WB: 1/500-1/1000
Protein Function
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 3.0 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

ICOS Tbio Inducible T-cell costimulator (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant ICOS Antibody (Ab109267) - Western Blot
All lanes: Recombinant ICOS Antibody (Ab109267) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 23 kDa
Observed band size: 23 kDa
Exposure time: 18.8 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0708937 Certificate of Analysis Jul 29, 2024 Ab109267
ZJ24F0708936 Certificate of Analysis Jul 29, 2024 Ab109267

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