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P4HB Antibody - Primary antibody, specific to P4HB, Rabbit IgG

COA COA
    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab119767
Grouped product items
SKU Size
Availability
 Price Qty
Ab119767-10μl
10μl
5
$66.90
Ab119767-50μl
50μl
3
$199.90
Ab119767-100μl
100μl
2
$299.90
Ab119767-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

pAb; Rabbit anti Human P4HB Antibody; WB; Unconjugated

View related series
Click to view target information: P4HB
Accession#:P07237 (2) Gene ID:5034 (2) P4HB (2)

Basic Description

Product Name P4HB Antibody - Primary antibody, specific to P4HB, Rabbit IgG
Synonyms Cellular thyroid hormone-binding protein | collagen prolyl 4-hydroxylase beta | DSI | ERBA2L | GIT | glutathione-insulin transhydrogenase | P4HB | P4Hbeta | p55 | PDI | PDIA1 | PDIA1procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase)
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, See COA
Host species Rabbit
Specificity P4HB
Immunogen Recombinant PDI expressed in E.coli (AA 216-465)
Positive Control WB: Hep G2, MCF7, HEK293, A431 and HeLa cell lysates.
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human P4HB Antibody, Polyclonal, could be used for WB and so on.
Application:
WB: 0.5-2 µg/mL
Protein Function
This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150kDa
Purification Method Antigen affinity purified and protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

P4HB Tchem Protein disulfide-isomerase (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

P4HB Antibody (Ab119767) - Western Blot
All lanes: P4HB Antibody (Ab119767) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 57 kDa
Observed band size: 59 kDa
Exposure time: 3.4 s

Application

Application Dilution info
WB

0.5-2 µg/mL

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001373 Certificate of Analysis Oct 18, 2023 Ab119767
ZJ23F1001374 Certificate of Analysis Oct 18, 2023 Ab119767

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