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p38 gamma/MAPK12 Antibody - Primary antibody, specific to MAPK12, Rabbit IgG

1 Citations COA COA
    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab119728
Grouped product items
SKU Size
Availability
 Price Qty
Ab119728-10μl
10μl
4
$86.90
Ab119728-50μl
50μl
1
$249.90
Ab119728-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
Ab119728-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

pAb; Rabbit anti Human p38 gamma/MAPK12 Antibody; WB, IHC; Unconjugated

View related series
Click to view target information: MAPK12
Accession#:P53778 (1) Gene ID:6300 (1) MAPK12 (1) p38 gamma (1)

Basic Description

Product Name p38 gamma/MAPK12 Antibody - Primary antibody, specific to MAPK12, Rabbit IgG
Synonyms EC 2.7.11 | ERK3 | ERK-6 | ERK6 | MAPK 12 | P38GAMMA | Extracellular signal-regulated kinase 6 | MAP kinase 12 | MAP kinase p38 gamma | MAPK12 | mitogen-activated protein kinase 12 | mitogen-activated protein kinase 3 | Mitogen-activated protein kinase p3
Specifications & Purity ExactAb™, Validated, Carrier Free, 0.4 mg/mL
Host species Rabbit
Specificity MAPK12
Immunogen A synthetic peptide derived from human MAPK12 (AA 106-131).
Positive Control WB: THP-1, K562 and C6 cell lysates. IHC：Human breast cancer tissue.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human p38 gamma/MAPK12 Antibody, Polyclonal, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/2000
IHC: 1/50-1/100
Protein Function
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration 0.4 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

MAPK12 Tchem Mitogen-activated protein kinase 12 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

p38 gamma/MAPK12 Antibody (Ab119728) - Western Blot
All lanes: p38 gamma/MAPK12 Antibody (Ab119728) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 42 kDa
Observed band size: 41 kDa
Exposure time: 150.0 s

p38 gamma/MAPK12 Antibody (Ab119728) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p38 gamma/MAPK12 Antibody (Ab119728). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
WB

1/500-1/2000
IHC

1/50 - 1/100

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404139 Certificate of Analysis Apr 03, 2024 Ab119728
ZJ23F1202128 Certificate of Analysis Dec 20, 2023 Ab119728
ZJ23F1202145 Certificate of Analysis Dec 20, 2023 Ab119728

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Citations of This Product

How to Cite Aladdin Scientific Products?
1. Zhu P,Qian J,Xu Z,Meng C,Liu J,Shan W,Zhu W,Wang Y,Yang Y,Zhang W,Zhang Y,Ling Y.  (2020)  Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling..  J Nat Prod,  83  (10.0): (3041-3049). 

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