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Crenezumab (anti-Amyloid Beta) - Primary antibody, specific to APP, >95% (SDS-PAGE&SEC), high purity, Human IgG4SP, INHIBITOR of Beta amyloid A4 protein inhibitor, INHIBITOR of Beta amyloid A4 protein inhibitor

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab175499
Grouped product items
SKU Size
Availability
 Price Qty
Ab175499-100μg
100μg
10
$109.90
Ab175499-1mg
1mg
4
$519.90
Ab175499-5mg
5mg
1
$1,399.90
Ab175499-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: APP
Accession#:P05067 (15) Amyloid Beta (12) APP (15) Gene ID:351 (15)

Basic Description

Product Name Crenezumab (anti-Amyloid Beta) - Primary antibody, specific to APP, >95% (SDS-PAGE&SEC), high purity, Human IgG4SP, INHIBITOR of Beta amyloid A4 protein inhibitor
Synonyms A4_HUMAN antibody | AAA antibody | ABETA antibody | ABPP antibody | AD1 antibody | AICD-50 antibody | AICD-57 antibody | AICD-59 antibody | AID(50) antibody | AID(57) antibody | Alzheimer disease amyloid protein antibody | AID(59) antibody | amyloid beta
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity APP
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Beta amyloid A4 protein inhibitor
Product Description

Crenezumab (anti-Amyloid Beta) is a fully humanized anti-Aβ monoclonal antibody that binds multiple forms of Aβ, such as soluble, oligomeric and fibrillar, for use in Alzheimer's disease research.

Purity

>95% (SDS-PAGE&SEC)

Endotoxin Level

< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 143.58 kDa
Purification Method Protein A purified
Purity >95% (SDS-PAGE&SEC)
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1095207-05-8

Associated Targets(Human)

APP Tclin Amyloid-beta A4 protein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Crenezumab (anti-Amyloid Beta) (Ab175499) - ELISA
Immobilized AB(1-42)-QY-monomer at 2.0 μg/mL can bind Crenezumab (anti-Amyloid Beta) (Ab175499) with the EC₅₀ of 0.48 μg/mL.

Crenezumab (anti-Amyloid Beta) (Ab175499) - SEC
The purity of Crenezumab (anti-Amyloid Beta) (Ab175499) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607160 Certificate of Analysis Jun 21, 2024 Ab175499
ZJ24F0607159 Certificate of Analysis Jun 21, 2024 Ab175499
ZJ24F0607158 Certificate of Analysis Jun 21, 2024 Ab175499

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