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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175861-100μg
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100μg |
10
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$79.90
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Ab175861-1mg
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1mg |
4
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$387.90
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|
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Ab175861-5mg
|
5mg |
1
|
$927.90
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|
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Ab175861-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,467.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Gantenerumab (anti-Amyloid Beta) - Primary antibody, specific to APP, >95%, high purity, Human IgG1, BINDING AGENT of Beta amyloid A4 protein binding agent |
|---|---|
| Synonyms | A4_HUMAN antibody | AAA antibody | ABETA antibody | ABPP antibody | AD1 antibody | AICD-50 antibody | AICD-57 antibody | AICD-59 antibody | AID(50) antibody | AID(57) antibody | AID(59) antibody | Alzheimer disease amyloid protein antibody | amyloid beta |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | APP |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of Beta amyloid A4 protein binding agent |
| Product Description |
Gantenerumab (anti-Amyloid Beta) is a fully human anti-amyloid-β (Aβ) IgG1 monoclonal antibody demonstrates sustained cerebral amyloid-β binding. Gantenerumab (anti-Amyloid Beta) can be used for Alzheimer's disease research. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 53.4 kDa (Heavy Chain), under reducing conditions; 177.4 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1043556-46-2 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Gantenerumab (anti-Amyloid Beta) (Ab175861) - ELISA
Immobilized hu-Amyloid β-Peptide (1-42) at 2 μg/mL can bind Gantenerumab (anti-Amyloid Beta) (Ab175861) with the EC50 of 16.77 ng/mL.
Gantenerumab (anti-Amyloid Beta) (Ab175861) - ELISA
Immobilized hu-Amyloid β-Peptide (1-40) at 2 μg/mL can bind Gantenerumab (anti-Amyloid Beta) (Ab175861) with the EC₅₀ of 5.96 ng/mL.
Gantenerumab (anti-Amyloid Beta) (Ab175861) - SEC
The purity of Gantenerumab (anti-Amyloid Beta) (Ab175861) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 07, 2025 | Ab175861 | |
| Certificate of Analysis | Mar 08, 2024 | Ab175861 | |
| Certificate of Analysis | Mar 08, 2024 | Ab175861 | |
| Certificate of Analysis | Mar 08, 2024 | Ab175861 |
Starting at $109.90
Starting at $109.90
Starting at $109.90