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Donanemab (anti-Amyloid Beta) - Primary antibody, specific to APP, >95%, high purity, Human IgG1, DISRUPTING AGENT of Beta amyloid A4 protein disrupting agent, DISRUPTING AGENT of Beta amyloid A4 protein disrupting agent

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175512
Grouped product items
SKU Size
Availability
Price Qty
Ab175512-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab175512-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
Ab175512-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$869.90
Ab175512-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,379.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Donanemab (anti-Amyloid Beta) - Primary antibody, specific to APP, >95%, high purity, Human IgG1, DISRUPTING AGENT of Beta amyloid A4 protein disrupting agent
Synonyms A4_HUMAN antibody | AAA antibody | ABETA antibody | ABPP antibody | AD1 antibody | AICD-50 antibody | AICD-57 antibody | AICD-59 antibody | AID(50) antibody | AID(57) antibody | AID(59) antibody | Alzheimer disease amyloid protein antibody | amyloid beta
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity APP
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type DISRUPTING AGENT
Mechanism of action DISRUPTING AGENT of Beta amyloid A4 protein disrupting agent
Product Description

Donanemab (anti-Amyloid Beta) is a humanized IgG1 monoclonal antibody directed at an N‐terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab (anti-Amyloid Beta) has the potential for early Alzheimer's disease research.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145.36 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1931944-80-7

Associated Targets(Human)

APP Tclin Amyloid-beta A4 protein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Brentuximab vedotin (anti-Amyloid Beta) (Ab175512) - ELISA
Immobilized Recombinant N3PG-Aβ oligomer (ZTSH) protein at 2.0 μg/mL can bind Brentuximab vedotin (anti-Amyloid Beta) (Ab175512) with the EC₅₀ of 135.5 ng/mL.

Brentuximab vedotin (anti-Amyloid Beta) (Ab175512) - SEC
The purity of Brentuximab vedotin (anti-Amyloid Beta) (Ab175512) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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Solution Calculators

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