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Lecanemab (anti-Amyloid Beta) - Primary antibody, specific to APP, >95%, high purity, Human IgG1, INHIBITOR of Beta amyloid A4 protein inhibitor, INHIBITOR of Beta amyloid A4 protein inhibitor

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175575
Grouped product items
SKU Size
Availability
 Price Qty
Ab175575-100μg
100μg
10
$89.90
Ab175575-1mg
1mg
4
$429.90
Ab175575-5mg
5mg
1
$1,099.90
Ab175575-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,749.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: APP
Accession#:P05067 (15) Amyloid Beta (12) APP (15) Gene ID:351 (15)

Basic Description

Product Name Lecanemab (anti-Amyloid Beta) - Primary antibody, specific to APP, >95%, high purity, Human IgG1, INHIBITOR of Beta amyloid A4 protein inhibitor
Synonyms A4_HUMAN antibody | AAA antibody | ABETA antibody | ABPP antibody | AD1 antibody | AICD-50 antibody | AICD-57 antibody | AICD-59 antibody | AID(50) antibody | AID(57) antibody | AID(59) antibody | Alzheimer disease amyloid protein antibody | amyloid beta
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity APP
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Beta amyloid A4 protein inhibitor
Product Description

Lecanemab (anti-Amyloid Beta) is a humanized IgG1 anti-soluble aggregated amyloid beta (Aβ) monoclonal antibody. Lecanemab (anti-Amyloid Beta) shows activity across oligomers, protofibrils and insoluble fibrils. Lecanemab (anti-Amyloid Beta) can be used for the research of Alzheimer's Disease.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 25.7 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 216.7 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1260393-98-3

Associated Targets(Human)

APP Tclin Amyloid-beta A4 protein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Lecanemab (anti-Amyloid Beta) (Ab175575) - Flow Cytometry
Flow Cytometry analysis of HUVEC cells labelling Amyloid Beta (red) with Lecanemab (anti-Amyloid Beta) (Ab175575). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Lecanemab (anti-Amyloid Beta) (Ab175575) - ELISA
Immobilized hu-Amyloid β-Peptide (1-40) at 2.0 μg/mL can bind Lecanemab (anti-Amyloid Beta) (Ab175575) with the EC₅₀ of 220.6 ng/mL.

Lecanemab (anti-Amyloid Beta) (Ab175575) - SEC
The purity of Lecanemab (anti-Amyloid Beta) (Ab175575) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303924 Certificate of Analysis Mar 29, 2024 Ab175575
ZJ24F0303923 Certificate of Analysis Mar 29, 2024 Ab175575
ZJ24F0303922 Certificate of Analysis Mar 29, 2024 Ab175575

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