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Recombinant p21 Antibody - Primary antibody, specific to CDKN1A, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab119615
Grouped product items
SKU Size
Availability
Price Qty
Ab119615-10μl
10μl
4
$99.90
Ab119615-50μl
50μl
2
$297.90
Ab119615-100μl
100μl
1
$387.90

Recombinant; Rabbit anti Human p21 Antibody; WB; Unconjugated

Basic Description

Product Name Recombinant p21 Antibody - Primary antibody, specific to CDKN1A, Rabbit IgG
Synonyms p21 Rabbit mAb | CDKN1A | CAP20 | CDKN1 | CIP1 | MDA6 | PIC1 | SDI1 | WAF1 | Cyclin-dependent kinase inhibitor 1 | CDK-interacting protein 1 | Melanoma differentiation-associated protein 6 | MDA-6 | p21 | CAP20 antibody | CDK-interacting protein 1 antibod
Specifications & Purity ExactAb™, Validated, Recombinant, 1.5 mg/mL
Host species Rabbit
Specificity CDKN1A
Immunogen A synthetic peptide derived from human p21 (AA 148-164).
Positive Control WB: MCF7, HUVEC, Hep G2, HeLa, A549, A431 and NIH/3T3 cell lysates
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Note 本产品即将售完下架,替代产品为 Ab119613
Product Description

Rabbit anti Human p21 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Immunogen affinity purified
Shape Liquid
Concentration 1.5 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CDKN1A Tchem Cyclin-dependent kinase inhibitor 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CDKN1A Tchem CDK-interacting protein 1 (92 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant p21 Antibody (Ab119615) - Western Blot
All lanes: Recombinant p21 Antibody (Ab119615) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 21 kDa
Observed band size: 20 kDa
Exposure time: 6.6 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404304 Certificate of Analysis Apr 09, 2024 Ab119615
ZJ23F0800957 Certificate of Analysis Sep 04, 2023 Ab119615
ZJ23F0800958 Certificate of Analysis Sep 04, 2023 Ab119615

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