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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab110172-10μl
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10μl |
2
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$66.90
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Ab110172-50μl
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50μl |
1
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$199.90
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Ab110172-100μl
|
100μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$319.90
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Ab110172-1ml
|
1ml |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,699.90
|
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Recombinant; Rabbit anti Human IL-23 Antibody; WB; Unconjugated
| Product Name | Recombinant IL-23 Antibody - Primary antibody, specific to IL23A, Rabbit IgG |
|---|---|
| Synonyms | IL-23 p19/IL-12 p40 | IL23 | IL-23 | IL-23A | IL-23-A | IL-23p19 | IL-23p19/IL-12p40 | IL23P19P19 | interleukin 23 p19 subunit | interleukin 23, alpha subunit p19 | interleukin-23 subunit alpha | Interleukin-23 subunit p19 | JKA3 induced upon T-cell activ |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 1.55 mg/mL |
| Host species | Rabbit |
| Specificity | IL23A |
| Immunogen | A synthetic peptide derived from human IL23 (AA 118-189) |
| Positive Control | WB: Raji, K562, THP-1, NIH/3T3 and C6 cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human IL-23 Antibody, Recombinant, could be used for WB and so on. Application: Protein Function: Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | 1.55 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Recombinant IL-23 Antibody (Ab110172) - Western Blot
All lanes: Recombinant IL-23 Antibody (Ab110172) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 21 kDa
Observed band size: 23 kDa
Exposure time: 50.0 s
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 14, 2024 | Ab110172 | |
| Certificate of Analysis | May 14, 2024 | Ab110172 |