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CD3 Mouse mAb - Primary antibody, specific to CD3, Mouse IgG1

COA COA
    Application:
  • Animal Model
  • Depletion
  • Flow Cytometry
  • Functional Assay
  • Inhibition
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: UCHT1
  • Conjugation: Unconjugated
In stock
Item Number
Ab094427
Grouped product items
SKU Size
Availability
 Price Qty
Ab094427-10μg
10μg
9
$19.90
Ab094427-50μg
50μg
4
$29.90
Ab094427-100μg
100μg
2
$39.90
Ab094427-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$369.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (UCHT1); Mouse anti Human CD3 Antibody; Flow, in vivo T cell depletion in humanized mice, ex vivo T cell inhibition for xenographs; Unconjugated

View related series
Click to view target information: CD3E
Accession#:P07766 (33) CD3 (44) CD3E (48) Flow Cytometry (1158) Gene ID: 916 (11) TCRE (12)

Basic Description

Product Name CD3 Mouse mAb - Primary antibody, specific to CD3, Mouse IgG1
Synonyms CD3epsilon | IMD18 | CD3 epsilon | CD3e antigen | CD3e antigen, epsilon polypeptide (TiT3 complex) | CD3e molecule, epsilon (CD3-TCR complex) | CD3e | CD3-epsilon | FLJ18683 | T3E | T-cell antigen receptor complex, epsilon subunit of T3 | T-cell surface a
Specifications & Purity Carrier Free, Azide Free, Validated, ≥95%(SDS-PAGE), See COA
Host species Mouse
Specificity CD3
Immunogen Human CD3ε
Conjugation Unconjugated
Grade Azide Free, Carrier Free, Validated
Product Description

Mouse anti Human CD3 Antibody, Monoclonal (UCHT1), could be used for Flow, in vivo T cell depletion in humanized mice, ex vivo T cell inhibition for xenographs and so on.

Application

Flow: Use at an assay dependent concentration.

in vivo T cell depletion in humanized mice: Use at an assay dependent concentration.
ex vivo T cell inhibition for xenographs: Use at an assay dependent concentration.

Protein Function

The CD3 complex mediates signal transduction.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD3 Mouse mAb (Ab094427) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 with CD3 Mouse mAb (Ab094427) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Biotin) (Ab180306) (left panel) and detected with SA-PE (rp156150).

CD3 Mouse mAb (Ab094427) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD3 (red) with CD3 Mouse mAb (Ab094427) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow Cytometry

Use at an assay dependent concentration.
in vivo T cell depletion in humanized mice

Use at an assay dependent concentration
ex vivo T cell inhibition for xenographs

Use at an assay dependent concentration

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607397 Certificate of Analysis Jun 26, 2024 Ab094427
ZJ24F0607396 Certificate of Analysis Jun 26, 2024 Ab094427
ZJ24F0607395 Certificate of Analysis Jun 26, 2024 Ab094427

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