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Teplizumab (anti-CD3e) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD3E, >95%, high purity, Human IgG1, OTHER of T-cell surface glycoprotein CD3 epsilon chain other, OTHER of T-cell surface glycoprotein CD3 epsilon chain other

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170781
Grouped product items
SKU Size
Availability
Price Qty
Ab170781-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab170781-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$357.90
Ab170781-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$837.90
Ab170781-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,347.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Teplizumab (anti-CD3e) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD3E, >95%, high purity, Human IgG1, OTHER of T-cell surface glycoprotein CD3 epsilon chain other
Synonyms MGA-031 | PRV-031 | CD3 epsilon antibody | CD3e antibody | CD3e antigen antibody | CD3e antigen epsilon polypeptide (TiT3 complex) antibody | CD3E antigen epsilon polypeptide antibody | CD3E antigen, epsilon subunit antibody | CD3e molecule epsilon antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD3E
Application ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type OTHER
Mechanism of action OTHER of T-cell surface glycoprotein CD3 epsilon chain other
Product Description

Teplizumab (anti-CD3e) is a Fc receptor non-binding anti-human CD3 monoclonal antibody. Teplizumab (anti-CD3e) reduces the loss of beta-cell function. Teplizumab (anti-CD3e) can be used in the research of type 1 diabetes.

Purity

>95% (SDS-PAGE&SEC)

Endotoxin Level

< 1.0EU/mg


Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 25.8 kDa (Light Chain) & 50.5 kDa (Heavy Chain), under reducing conditions; 174.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 876387-05-2

Associated Targets(Human)

CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Teplizumab (anti-CD3e) (Ab170781) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD3e (red) with Teplizumab (anti-CD3e) (Ab170781). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Teplizumab (anti-CD3e) (Ab170781) - SEC
The purity of Teplizumab (anti-CD3e) (Ab170781) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001449 Certificate of Analysis Oct 26, 2023 Ab170781
ZJ23F1001450 Certificate of Analysis Oct 26, 2023 Ab170781

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