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免疫疾病靶点

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  1. Recombinant Human IL-2 Receptor Alpha Protein
      种属: 人(Human)    Accession #: P01589    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.2 ‑1.2 µg/mL in the presence of 30 ng/mL of recombinant human IL-2. 2. Immobilized Recombinant Human IL-2 Protein (rp156004) at 1 μg/mL can bind biotinylated Recombinant Human IL-2 Receptor Alpha Protein (rp147480).    
  2. Recombinant Human IL-6R Protein
      种属: 人(Human)    Accession #: P08887    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.    
  3. Recombinant Human CD47 Protein
      种属: 人(Human)    Accession #: Q08722    
      表达系统: HEK293    蛋白标签: C-hFc    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC50 of human CD47 Protein is 50.0 - 200.0 ng/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD47 Protein (rp144028) at 1 μg/mL can bind Magrolimab (anti-CD47) (Ab169323) with the EC50 of 10.34 ng/mL.    
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