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脑与神经疾病靶点

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  1. Recombinant Human IL-2 Receptor Alpha Protein
      种属: 人(Human)    Accession #: P01589    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.2 ‑1.2 µg/mL in the presence of 30 ng/mL of recombinant human IL-2. 2. Immobilized Recombinant Human IL-2 Protein (rp156004) at 1 μg/mL can bind biotinylated Recombinant Human IL-2 Receptor Alpha Protein (rp147480).    
  2. Recombinant Human IL-6R Protein
      种属: 人(Human)    Accession #: P08887    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Immobilized Recombinant Human IL-6 Protein at 2 μg/mL can bind Recombinant Human IL-6R Protein (rp147628) the EC50 is 8.0 - 24.0 ng/mL. 2. Measured by its ability to enhance the IL-6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10.0 - 60.0 ng/mL.3. Using the Octet RED System, the affinity constant (Kd) of Recombinant Human IL-6R Protein (rp147628) bound Anti-IL6R Antibody was 0.1 nM.    
  3. Recombinant Human Nectin-2/CD112 Protein
      种属: 人(Human)    Accession #: Q92692    
      表达系统: HEK293    蛋白标签: No tag     内毒素水平: <1.0 EU/μg    
      生物活性: Recombinant Human Nectin-2/CD112 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human DNAM-1/CD226 hFc has been identified as an interactor of Nectin-2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-2 and recombinant DNAM-1/CD226 hFc.    
  4. Recombinant Human CD33 Protein
      种属: 人(Human)    Accession #: P20138    
      表达系统: HEK293    蛋白标签: C-hFc & His    内毒素水平: <0.1 EU/μg    
      生物活性: 1、Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. The ED50 for this effect is 1‑4 µg/mL. 2、Immobilized Recombinant Human CD33 Protein (rp143966) at 2.0 μg/mL can bind Gemtuzumab (anti-CD33) (Ab175859). The ED50 for this effect is 391.3 ng/mL.    
  5. Recombinant Human IFN-alpha/beta R1 Protein
      种属: 人(Human)    Accession #: P17181    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <0.1 EU/μg    
      生物活性: Measured by its binding ability in a functional ELISA. When Recombinant Human IFN-alpha / beta R1 is present at 10 μg/mL, it binds to Recombinant Human IFN‑ alpha / beta R2 Fc Chimera in the presence of recombinant human IFN-alpha 2. The concentration of Recombinant Human IFN-alpha / beta R2 Fc Chimera that produces 50% of the optimal binding response is approximately 0.5-1.5 μg/mL.    
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