货号 (SKU)

包装规格

是否现货

价格

数量

Ab210972-10μg

10μg

现货

Ab210972-50μg

50μg

现货

Ab210972-100μg

100μg

现货

Ab210972-1mg

1mg

期货

基本信息

产品名称	Recombinant CD4 Antibody
别名	抗人CD4单克隆抗体 \| Anti-CD4抗体 \| CD4抗体
英文别名	CD_antigen: CD4 \| CD4 antigen (p55) \| CD4 antigen \| CD4 molecule \| CD4 receptor \| CD4 \| CD4mut \| T-cell surface antigen T4/Leu-3 \| T-cell surface glycoprotein CD4 \| CD 4 antibody \| CD4 (L3T4) antibody \| CD4 antibody \| CD4 antigen (p55) antibody \| CD4 anti
规格或纯度	无动物源, 无载体, 重组, ExactAb™, 已验证, 无叠氮钠, 高性能, ≥95%(SDS-PAGE), 见COA
生化机理	Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed:12089508, PubMed:16331979, PubMed:2214026, PubMed:9641677). Down-regulated by HIV-1 Vpu (PubMed:17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed:7909607)..
宿主种属	小鼠(Mouse)
特异性	Human CD4
种属反应性	人(Human)
免疫原	Human peripheral T cells
阳性对照	Flow Cytometry: Human peripheral blood lymphocytes
偶联	Unconjugated

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A purified
储存缓冲液	PBS, pH 7.4
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at 4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
分子类型	抗体

关联靶点（人）

CD4 Tclin T 细胞表面糖蛋白 CD4(T-cell surface glycoprotein CD4) (0 活性数据)

点击查看靶蛋白信息： CD4

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD4 Antibody (Ab210972)

Recombinant CD4 Antibody (Ab210972) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD4 with Recombinant CD4 Antibody (Ab210972) conjugated with biotin (right panel) at 1 μg/mL for 1 hour at 4°C, compared with Mouse IgG (Biotin) (Ab180306) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Flow Cytometry: Recombinant CD4 Antibody (Ab210972)

Recombinant CD4 Antibody (Ab210972) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD4 (red) with Recombinant CD4 Antibody (Ab210972) conjugated with biotin at 1 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, compared with Mouse IgG (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Recombinant CD4 Antibody (Ab210972)

Recombinant CD4 Antibody (Ab210972) - SEC
The purity of Recombinant CD4 Antibody (Ab210972) is more than 95% verified by HPLC.

应用

应用名称	稀释比例
Flow Cytometry	≤0.5 µg per million cells in 100 µl volume

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找到2个结果

批号(Lot Number)	证书类型	货号
ZJ25F0218618	分析证书	Ab210972
ZJ25F0218617	分析证书	Ab210972

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