基本信息

产品名称	Recombinant CD4 Antibody (PE-Cy7)
别名	抗人CD4单克隆抗体 \| Anti-CD4抗体 \| CD4抗体
英文别名	CD_antigen: CD4 \| CD4 antigen (p55) \| CD4 antigen \| CD4 molecule \| CD4 receptor \| CD4 \| CD4mut \| T-cell surface antigen T4/Leu-3 \| T-cell surface glycoprotein CD4 \| CD 4 antibody \| CD4 (L3T4) antibody \| CD4 antibody \| CD4 antigen (p55) antibody \| CD4 anti
规格或纯度	ExactAb™, 已验证, 5 μL/test
生化机理	Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1). Down-regulated by HIV-1 Vpu. Acts as a receptor for Human Herpes virus 7/HHV-7.
宿主种属	小鼠(Mouse)
特异性	CD4
种属反应性	人(Human)
阳性对照	Flow: Human peripheral blood lymphocytes
偶联	PE-Cy7
Excitation(nm)	Blue Laser(488nm), Green Laser(532nm), Yellow-Green Laser(561nm)
Emission(nm)	774nm
Ex/Em(nm)	Ex:565nm;Em:774nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	5 μL/test
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

CD4 Tclin T 细胞表面糖蛋白 CD4(T-cell surface glycoprotein CD4) (0 活性数据)

点击查看靶蛋白信息： CD4

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD4 Antibody (PE-Cy7) (Ab213138)

Recombinant CD4 Antibody (PE-Cy7) (Ab213138) - Flow Cytometry
Flow cytometry analysis of CD4 expression by human peripheral blood lymphocytes (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD4 Antibody (PE-Cy7) (Ab213138) at 5μL/test for 1 hour at 4°C. Left panel - Mouse IgG (PE-Cy7) (Ab190079).

Flow Cytometry: Recombinant CD4 Antibody (PE-Cy7) (Ab213138)

Recombinant CD4 Antibody (PE-Cy7) (Ab213138) - Flow Cytometry
Flow cytometry analysis of CD4 expression by human peripheral blood lymphocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD4 Antibody (PE-Cy7) (Ab213138) at 5μL/test for 1 hour at 4°C. Blue - Mouse IgG (PE-Cy7) (Ab190079). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	5 μL/test. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到3个结果

批号(Lot Number)	证书类型	货号
ZJ25F0218163	分析证书	Ab213138
ZJ25F0218162	分析证书	Ab213138
ZJ25F0218161	分析证书	Ab213138

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