货号 (SKU)

包装规格

是否现货

价格

数量

Ab176220-100μg

100μg

现货

Ab176220-1mg

1mg

现货

Ab176220-5mg

5mg

现货

Ab176220-10mg

10mg

期货

基本信息

产品名称	Adecatumumab (anti-EpCAM), 上皮细胞粘附分子抑制剂
别名	阿德木单抗 \| 阿德木单抗 (抗 EpCAM)
英文别名	17 1A antibody \| 323/A3 antibody \| Adenocarcinoma associated antigen antibody \| Adenocarcinoma-associated antigen antibody \| Antigen identified by monoclonal antibody AUA1 antibody \| AUA1 antibody \| CD326 antibody \| CD326 antigen antibody \| Cell surface g
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	EPCAM
种属反应性	人(Human)
偶联	Unconjugated
作用类型	抑制剂
作用机制	上皮细胞粘附分子抑制剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	27.2 kDa (Light Chain) & 51.4 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions.
纯化方法	Protein A purified
纯度	>95%
物理外观	Liquid
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	503605-66-1
分子类型	抗体

关联靶点（人）

EPCAM Tbio 上皮细胞粘附分子(Epithelial cell adhesion molecule) (0 活性数据)

点击查看靶蛋白信息： EPCAM

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Adecatumumab (anti-EpCAM) (Ab176220)

Adecatumumab (anti-EpCAM) (Ab176220) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling EpCAM (red) with Adecatumumab (anti-EpCAM) (Ab176220). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Adecatumumab (anti-EpCAM) (Ab176220)

Adecatumumab (anti-EpCAM) (Ab176220) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling EpCAM (red) with Adecatumumab (anti-EpCAM) (Ab176220). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

SEC: Adecatumumab (anti-EpCAM) (Ab176220)

Adecatumumab (anti-EpCAM) (Ab176220) - SEC
The purity of Adecatumumab (anti-EpCAM) (Ab176220) is more than 95% verified by HPLC.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到4个结果

批号(Lot Number)	证书类型	货号
ZJ24F1113346	分析证书	Ab176220
ZJ24F1113345	分析证书	Ab176220
ZJ24F1113344	分析证书	Ab176220
ZJ24F0404305	分析证书	Ab176220

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引用文献

1. Simon, B B and 5 more authors.. (1990) Epithelial glycoprotein is a member of a family of epithelial cell surface antigens homologous to nidogen, a matrix adhesion protein.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2108441]
2. Szala, S S and 6 more authors.. (1990) Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2333300]
3. Strnad, J J and 9 more authors.. (1989) Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA.. Cancer research, (15): [PMID:2463074]
4. Perez, M S MS and Walker, L E LE.. (1989) Isolation and characterization of a cDNA encoding the KS1/4 epithelial carcinoma marker.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:2469722]
5. Linnenbach, A J AJ and 7 more authors.. (1989) Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2911574]
6. Björk, P P and 8 more authors.. (1993) Isolation, partial characterization, and molecular cloning of a human colon adenocarcinoma cell-surface glycoprotein recognized by the C215 mouse monoclonal antibody.. The Journal of biological chemistry, (15): [PMID:7693697]
7. Linnenbach, A J AJ and 7 more authors.. (1993) Retroposition in a family of carcinoma-associated antigen genes.. Molecular and cellular biology, [PMID:8382772]
8. Chong, J M JM and Speicher, D W DW.. (2001) Determination of disulfide bond assignments and N-glycosylation sites of the human gastrointestinal carcinoma antigen GA733-2 (CO17-1A, EGP, KS1-4, KSA, and Ep-CAM).. The Journal of biological chemistry, (23): [PMID:11080501]
9. Münz, Markus M and 5 more authors.. (2004) The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation.. Oncogene, (29): [PMID:15195135]
10. Münz, Markus M, Zeidler, Reinhard R and Gires, Olivier O.. (2005) The tumour-associated antigen EpCAM upregulates the fatty acid binding protein E-FABP.. Cancer letters, (8): [PMID:15922867]
11. Ladwein, Markus M and 8 more authors.. (2005) The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7.. Experimental cell research, (1): [PMID:16054130]
12. Munz, Markus M, Fellinger, Karin K, Hofmann, Tanja T, Schmitt, Barbel B and Gires, Olivier O.. (2008) Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM.. Frontiers in bioscience : a journal and virtual library, (1): [PMID:18508581]
13. Sivagnanam, Mamata M and 15 more authors.. (2008) Identification of EpCAM as the gene for congenital tufting enteropathy.. Gastroenterology, [PMID:18572020]
14. Ligtenberg, Marjolijn J L MJ and 17 more authors.. (2009) Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.. Nature genetics, [PMID:19098912]
15. Ng, Valerie Y VY, Ang, Sheu Ngo SN, Chan, Jia Xin JX and Choo, Andre B H AB.. (2010) Characterization of epithelial cell adhesion molecule as a surface marker on undifferentiated human embryonic stem cells.. Stem cells (Dayton, Ohio), [PMID:19785009]
16. Lu, Tung-Ying TY and 6 more authors.. (2010) Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells.. The Journal of biological chemistry, (19): [PMID:20064925]

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Adecatumumab (anti-EpCAM), 上皮细胞粘附分子抑制剂

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基本信息

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质检证书（CoA,COO,BSE/TSE 和分析图谱)

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引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

Adecatumumab (anti-EpCAM), 上皮细胞粘附分子抑制剂

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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溶液计算器

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