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Edrecolomab (anti-EpCAM), 上皮细胞粘附分子交联剂的交联剂

Edrecolomab (anti-EpCAM), 上皮细胞粘附分子交联剂的交联剂

级别和纯度:

≥95%(SDS-PAGE&SEC-HPLC)
见COA

应用:

ELISA
Flow Cytometry

宿主种属: 小鼠(Mouse)
种属反应性: 人(Human)
亚型: Mouse IgG2a
偶联: Unconjugated

有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU)	包装规格	是否现货
Ab175518-100μg	100μg	现货
Ab175518-1mg	1mg	现货
Ab175518-5mg	5mg	期货
Ab175518-10mg	10mg	期货

查看相关系列

点击查看靶蛋白信息: EPCAM

Accession#:P16422 (16) Epcam (20) Gene ID:4072 (17)

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基本信息

产品名称	Edrecolomab (anti-EpCAM), 上皮细胞粘附分子交联剂的交联剂
别名	依决洛单抗 \| EpCAM抗体 \| EpCAM单克隆抗体 \| EpCAM药靶抗体 \| CD326抗体 \| CD326单克隆抗体 \| CD326药靶抗体 \| 17-1A抗体 \| 17-1A单克隆抗体 \| 17-1A药靶抗体
英文别名	17 1A antibody \| 323/A3 antibody \| Adenocarcinoma associated antigen antibody \| Adenocarcinoma-associated antigen antibody \| Antigen identified by monoclonal antibody AUA1 antibody \| AUA1 antibody \| CD326 antibody \| CD326 antigen antibody \| Cell surface g
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
生化机理	May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
宿主种属	小鼠(Mouse)
特异性	EPCAM
种属反应性	人(Human)
偶联	Unconjugated
作用类型	交联剂
作用机制	上皮细胞粘附分子交联剂的交联剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG2
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	PBS, pH 7.4,Contains no stabilizers or preservatives.
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	Store at -80℃ for 12 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS编号和信息	156586-89-9
分子类型	抗体

关联靶点（人）

EPCAM Tbio 上皮细胞粘附分子(Epithelial cell adhesion molecule) (0 活性数据)

点击查看靶蛋白信息： EPCAM

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Edrecolomab (anti-EpCAM) (Ab175518)

Edrecolomab (anti-EpCAM) (Ab175518) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling EpCAM (red) with Edrecolomab (anti-EpCAM) (Ab175518) at 1 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Edrecolomab (anti-EpCAM) (Ab175518)

Edrecolomab (anti-EpCAM) (Ab175518) - ELISA
Immobilized Recombinant Human EPCAM protein (rp170132) at 1.0 μg/mL can bind Edrecolomab (anti-EpCAM) (Ab175518) with the EC50 of 0.74 μg/mL.