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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab110155-10μl |
10μl |
现货 ![]() |
| |
| Ab110155-50μl |
50μL |
现货 ![]() |
| |
| Ab110155-100μl |
100μL |
现货 ![]() |
| |
| Ab110155-1ml |
1ml |
期货 ![]() |
|
| 产品名称 | IL22 Mouse mAb |
|---|---|
| 别名 | 白介素22抗体 | 白介素22单克隆抗体 | IL22抗体 | IL22单克隆抗体 | CD334抗体 | CD334单克隆抗体 |
| 英文别名 | Cytokine Zcyto18 | IL-10-related T-cell-derived inducible factor | IL22 | IL-22 | IL-D110 | IL-TIF | ILTIFIL-10-related T-cell-derived-inducible factor | IL-TIFMGC79382 | interleukin 22 | interleukin-22 | MGC79384 | TIFa | TIFIL-23 | zcyto18 | Cytokine Zc |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 高性能, 见COA |
| 生化机理 | Cytokine that contributes to the inflammatory response in vivo. |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | IL22 |
| 种属反应性 | 人(Human),大鼠(Rat),小鼠(Mouse) |
| 免疫原 | Recombinant IL22 expressed in E.coli (AA 34-179) |
| 阳性对照 | WB: CTLL-2, MOLT-4, Jurkat, HeLa, NIH/3T3 and C6 cell lysates. |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | C6 |
| Format | Whole IgG |
| 亚型 | Mouse IgG2a |
| 轻链亚型 | kappa |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein A + Protein G purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH7.4 |
| 防腐剂 | 0.05% Proclin 300 |
| 浓度 | 见COA |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 4℃ 短期储存(1-2 周)。-20℃长期保存(24 个月)。收货后建议分装。避免冷冻/解冻循环。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
IL22 Mouse mAb (Ab110155) - Western Blot
All lanes: IL22 Mouse mAb (Ab110155) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 14 kDa
Exposure time: 9.9 s
| 应用名称 | 稀释比例 |
|---|---|
| WB |
0.01-2 µg/mL
|
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab110155 | |
| 分析证书 | Ab110155 | |
| 分析证书 | Ab110155 | |
| 分析证书 | Ab110155 | |
| 分析证书 | Ab110155 | |
| 分析证书 | Ab110155 | |
| 分析证书 | Ab110155 |
| 1. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C et al.. (2003) The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.. Genome Res, 13 (10): (2265-70). [PMID:12975309] |
| 2. Xie, M H MH and 8 more authors.. (2000) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R.. The Journal of biological chemistry, (6): [PMID:10875937] |
| 3. Dumoutier, L L, Van Roost, E E, Colau, D D and Renauld, J C JC.. (2000) Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor.. Proceedings of the National Academy of Sciences of the United States of America, (29): [PMID:10954742] |
| 4. Dumoutier, L L, Van Roost, E E, Ameye, G G, Michaux, L L and Renauld, J C JC.. (2000) IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes.. Genes and immunity, [PMID:11197690] |
| 5. Nagem, R A P RA and 5 more authors.. (2002) Crystallization and synchrotron X-ray diffraction studies of human interleukin-22.. Acta crystallographica. Section D, Biological crystallography, [PMID:11856845] |
| 6. Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161] |
| 7. Brand, Stephan S and 14 more authors.. (2007) IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro.. American journal of physiology. Gastrointestinal and liver physiology, [PMID:17204547] |
| 8. Jones, Brandi C BC, Logsdon, Naomi J NJ and Walter, Mark R MR.. (2008) Structure of IL-22 bound to its high-affinity IL-22R1 chain.. Structure (London, England : 1993), (10): [PMID:18599299] |
| 9. Akil, Hussein H and 12 more authors.. (2015) IL22/IL-22R pathway induces cell survival in human glioblastoma cells.. PloS one, [PMID:25793261] |
| 10. Moniruzzaman, Md M, Wang, Ran R, Jeet, Varinder V, McGuckin, Michael A MA and Hasnain, Sumaira Z SZ.. (2019) Interleukin (IL)-22 from IL-20 Subfamily of Cytokines Induces Colonic Epithelial Cell Proliferation Predominantly through ERK1/2 Pathway.. International journal of molecular sciences, (15): [PMID:31311100] |