货号 (SKU)

包装规格

是否现货

价格

数量

Ab109567-10μl

10μl

现货

Ab109567-50μl

50μL

现货

Ab109567-100μl

100μL

期货

Ab109567-1ml

1ml

期货

基本信息

产品名称	IGFBP3 Mouse mAb
别名	胰岛素样生长因子结合蛋白3(IGFBP3)单克隆抗体 \| IGFBP3 小鼠单克隆抗体 \| IGFBP3 小鼠单抗
英文别名	Acid stable subunit of the 140 K IGF complex antibody \| Binding protein 29 antibody \| Binding protein 53 antibody \| BP 53 antibody \| BP53 antibody \| Growth hormone dependent binding proteinantibody \| IBP 3 antibody \| IBP3 antibody \| IGF binding protein 3
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	小鼠(Mouse)
特异性	IGFBP3
种属反应性	人(Human)
免疫原	Recombinant IGFBP3 expressed in E.coli (AA 135-277)
阳性对照	WB: A431 and Hep G2 cell lysates.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	D15
Format	Whole IgG
亚型	Mouse IgG1
轻链亚型	kappa
SDS-PAGE	150 kDa
纯化方法	Protein A + Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, 50% Glycerol, 0.05% Proclin 300, pH7.4
防腐剂	0.05% Proclin 300
浓度	见COA
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	4℃ 短期储存（1-2 周）。-20℃长期保存（24 个月）。收货后建议分装。避免冷冻/解冻循环。
分子类型	抗体

关联靶点（人）

IGFBP3 Tchem 胰岛素类生长因子结合蛋白 3(Insulin-like growth factor-binding protein 3) (0 活性数据)

点击查看靶蛋白信息： IGFBP3

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Western Blot: IGFBP3 Mouse mAb (Ab109567)

IGFBP3 Mouse mAb (Ab109567) - Western Blot
All lanes: IGFBP3 Mouse mAb (Ab109567) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 30 kDa
Observed band size: 37 kDa
Exposure time: 9.1 s

应用

应用名称	稀释比例
WB	0.5-2µg/mL

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到5个结果

批号(Lot Number)	证书类型	货号
ZJ23F1201972	分析证书	Ab109567
ZJ23F1201973	分析证书	Ab109567
ZJ23F1201974	分析证书	Ab109567
ZJ24F1011943	分析证书	Ab109567
ZJ24F1011887	分析证书	Ab109567

技术文档和文章

石蜡样品的免疫组化染色方案（IHC-P）

Categories: 实验方案（Protocols）

探索主题:

单克隆抗体石蜡切片免疫组化染色

蛋白质印迹的一抗选择指南

Categories: 实验方案（Protocols）

探索主题:

重组抗体单克隆抗体多克隆抗体蛋白质印迹内参抗体一抗选择

Guidelines of Primary Antibodies for Western Blotting

Categories: 实验方案（Protocols）

探索主题:

Western blotting Monoclonal antibodies Recombinant Antibodies Polyclonal Antibodies Primary Antibodies Selection Loading Controls

Guidelines of Primary Antibodies for Western Blotting

Categories: 实验方案（Protocols）

探索主题:

Western blotting Monoclonal antibodies Recombinant Antibodies Polyclonal Antibodies Primary Antibodies Selection Loading Controls

高分子量蛋白质印迹法

Categories: 实验方案（Protocols）

探索主题:

免疫印迹生物缓冲液蛋白质印迹高分子量蛋白大分子蛋白蛋白质电泳 WB抗体

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

探索主题:

Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

探索主题:

Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

探索主题:

Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

Protocol of Western Blotting For High Molecular Weights

Categories: 实验方案（Protocols）

探索主题:

Western blotting Biological buffer Immunoblotting Protein Electrophoresis High Molecular Weights large molecular proteins WB antibody

引用文献

1. Scherer SW, Cheung J, MacDonald JR, Osborne LR, Nakabayashi K, Herbrick JA, Carson AR, Parker-Katiraee L, Skaug J, Khaja R et al.. (2003) Human chromosome 7: DNA sequence and biology.. Science, 300 (5620): (767-72). [PMID:12690205]
2. Evert Njomen,Hedeel G Evans,Samanthi H Gedara,Deborah L Heyl. (2015-07-29) Humanin Peptide Binds to Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) and Regulates Its Interaction with Importin-β.. Protein and peptide letters, 22 ((10)): (869-876). [PMID:26216267]
3. Cubbage, M L ML, Suwanichkul, A A and Powell, D R DR.. (1990) Insulin-like growth factor binding protein-3. Organization of the human chromosomal gene and demonstration of promoter activity.. The Journal of biological chemistry, (25): [PMID:1695633]
4. Zapf, J J and 7 more authors.. (1990) Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia.. The Journal of biological chemistry, (5): [PMID:1697583]
5. Roghani, M M, Segovia, B B, Whitechurch, O O and Binoux, M M.. (1991) Purification from human cerebrospinal fluid of insulin-like growth factor binding proteins (IGFBPs). Isolation of IGFBP-2, an altered form of IGFBP-3 and a new IGFBP species.. Growth regulation, [PMID:1726837]
6. Wood, W I WI and 7 more authors.. (1988) Cloning and expression of the growth hormone-dependent insulin-like growth factor-binding protein.. Molecular endocrinology (Baltimore, Md.), [PMID:2464130]
7. Thweatt, R R, Fleischmann, R R and Goldstein, S S.. (1993) Analysis of the primary structure of insulin-like growth factor binding protein-3 cDNA from Werner syndrome fibroblasts.. DNA sequence : the journal of DNA sequencing and mapping, [PMID:7508771]
8. Hillier, Ladeana W LW and 106 more authors.. (2003) The DNA sequence of human chromosome 7.. Nature, (10): [PMID:12853948]
9. Ikonen, Maaria M and 7 more authors.. (2003) Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis.. Proceedings of the National Academy of Sciences of the United States of America, (28): [PMID:14561895]
10. Bunkenborg, Jakob J, Pilch, Bartosz J BJ, Podtelejnikov, Alexandre V AV and Wiśniewski, Jacek R JR.. (2004) Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.. Proteomics, [PMID:14760718]
11. Zhang, Zemin Z and Henzel, William J WJ.. (2004) Signal peptide prediction based on analysis of experimentally verified cleavage sites.. Protein science : a publication of the Protein Society, [PMID:15340161]
12. (2005) Mecasermin rinfabate: insulin-like growth factor-I/insulin-like growth factor binding protein-3, mecaserimin rinfibate, rhIGF-I/rhIGFBP-3.. Drugs in R&D, [PMID:15777106]
13. Liu, Tao T and 6 more authors.. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.. Journal of proteome research, [PMID:16335952]
14. Chang, Yoon Soo YS and 7 more authors.. (2006) 9-cis retinoic acid induces insulin-like growth factor binding protein-3 through DR-8 retinoic acid responsive elements.. Cancer biology & therapy, [PMID:16760641]
15. Sjöblom, Tobias T and 28 more authors.. (2006) The consensus coding sequences of human breast and colorectal cancers.. Science (New York, N.Y.), (13): [PMID:16959974]
16. Williams, Rachel M RM, McDonald, Anna A, O'Savage, Martin M and Dunger, David B DB.. (2008) Mecasermin rinfabate: rhIGF-I/rhIGFBP-3 complex: iPLEX.. Expert opinion on drug metabolism & toxicology, [PMID:18363546]
17. Muzumdar, Radhika H RH and 12 more authors.. (2009) Humanin: a novel central regulator of peripheral insulin action.. PloS one, (22): [PMID:19623253]
18. and Kemp, Stephen F SF.. (2009) Insulin-like growth factor-I deficiency in children with growth hormone insensitivity: current and future treatment options.. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, [PMID:19627167]
19. Lue, YanHe Y and 10 more authors.. (2010) Opposing roles of insulin-like growth factor binding protein 3 and humanin in the regulation of testicular germ cell apoptosis.. Endocrinology, [PMID:19952275]
20. Ingermann, Angela R AR and 11 more authors.. (2010) Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer.. The Journal of biological chemistry, (24): [PMID:20353938]
21. Tagliabracci, Vincent S VS and 14 more authors.. (2015) A Single Kinase Generates the Majority of the Secreted Phosphoproteome.. Cell, (18): [PMID:26091039]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

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g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

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浓度 2 (C2)

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复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

IGFBP3 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

IGFBP3 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器