货号 (SKU)

包装规格

是否现货

价格

数量

Ab095464-10μg

10μg

现货

Ab095464-50μg

50μg

现货

Ab095464-100μg

100μg

现货

Ab095464-1mg

1mg

期货

基本信息

产品名称	CD86 Mouse mAb
别名	CD86小鼠单克隆抗体 \| CD86小鼠单抗
英文别名	Activation B7-2 antigen \| B70 \| BU63 \| CTLA-4 counter-receptor B7.2 \| FUN-1
规格或纯度	无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属	小鼠(Mouse)
特异性	CD86
种属反应性	人(Human)
免疫原	ARH 77 (B lymphoblastoid cell line).
阳性对照	Flow: Human peripheral blood monocyte.
偶联	Unconjugated

产品属性

克隆类型	单克隆抗体
克隆号	BU63
Format	Whole IgG
亚型	Mouse IgG1
SDS-PAGE	150 kDa
纯化方法	Protein G purified
物理外观	Liquid
储存缓冲液	10mM PBS, 0.1% Proclin 300, pH 7.2-7.4
防腐剂	0.1% Proclin 300
浓度	见COA
储存温度	2-8°C储存
运输条件	冰袋运输
稳定性与储存	4°C 下运输。4°C 长期保存（12 个月）。收货后建议分装。
分子类型	抗体

关联靶点（人）

CD86 Tclin T淋巴细胞活化抗原CD86(T-lymphocyte activation antigen CD86) (0 活性数据)

点击查看靶蛋白信息： CD86

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Anti-CD86 antibody (Ab095464)

Anti-CD86 antibody (Ab095464) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD86 (red) with Anti-CD86 antibody (Ab095464) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (AF647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	1μg/100w cells

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到3个结果

批号(Lot Number)	证书类型	货号
ZJ24F0202986	分析证书	Ab095464
ZJ23F1201931	分析证书	Ab095464
ZJ23F1201932	分析证书	Ab095464

技术文档和文章

利用甲醇通透法进行流式细胞术

Categories: 实验方案（Protocols）

探索主题:

流式细胞术流式抗体流式实验甲醇通透细胞分选细胞分型免疫研究细胞内抗原检测

Flow Cytometry Using Methanol Permeabilization

Categories: 实验方案（Protocols）

探索主题:

Flow Cytometry FlowCytometry methanolpermeabilization flowcytometryantibodies Cell Sorting Cell Typing Immunology Research Intracellular Antigen Detection

Flow Cytometry Using Methanol Permeabilization

Categories: 实验方案（Protocols）

探索主题:

Flow Cytometry FlowCytometry methanolpermeabilization flowcytometryantibodies Cell Sorting Cell Typing Immunology Research Intracellular Antigen Detection

可替换产品

引用文献

1. Vicente Rabaneda EF, Herrero-Beaumont G, Castañeda S. (2013) Update on the use of abatacept for the treatment of rheumatoid arthritis.. Expert Rev Clin Immunol, 9 (7): (599-621). [PMID:23899231]
2. Linsley PS, Brady W, Urnes M, Grosmaire LS, Damle NK, Ledbetter JA. (1991) CTLA-4 is a second receptor for the B cell activation antigen B7.. J Exp Med, 174 (3): (561-9). [PMID:1714933]
3. Engel, P P and 8 more authors.. (1994) The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen.. Blood, (1): [PMID:7520767]
4. Lanier, L L LL and 7 more authors.. (1995) CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:7527824]
5. Jellis, C L CL and 6 more authors.. (1995) Genomic organization of the gene coding for the costimulatory human B-lymphocyte antigen B7-2 (CD86).. Immunogenetics, [PMID:7541777]
6. Azuma, M M and 6 more authors.. (1993) B70 antigen is a second ligand for CTLA-4 and CD28.. Nature, (4): [PMID:7694153]
7. Freeman, G J GJ and 7 more authors.. (1993) Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation.. Science (New York, N.Y.), (5): [PMID:7694363]
8. Magistrelli, G G and 5 more authors.. (2001) Identification of an alternatively spliced variant of human CD86 mRNA.. Biochemical and biophysical research communications, (9): [PMID:11162656]
9. Schwartz, J C JC, Zhang, X X, Fedorov, A A AA, Nathenson, S G SG and Almo, S C SC.. (2001) Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.. Nature, (29): [PMID:11279501]
10. Chen, X X, Ji, Z L ZL and Chen, Y Z YZ.. (2002) TTD: Therapeutic Target Database.. Nucleic acids research, (1): [PMID:11752352]
11. Goto, Eiji E and 6 more authors.. (2003) c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity.. The Journal of biological chemistry, (25): [PMID:12582153]
12. Zhang, Xuewu X, Schwartz, Jean-Claude D JC, Almo, Steven C SC and Nathenson, Stanley G SG.. (2003) Crystal structure of the receptor-binding domain of human B7-2: insights into organization and signaling.. Proceedings of the National Academy of Sciences of the United States of America, (4): [PMID:12606712]
13. and Kremer, Joel M JM.. (2005) Selective costimulation modulators: a novel approach for the treatment of rheumatoid arthritis.. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, [PMID:16357751]
14. Hervey, Pauline S PS and Keam, Susan J SJ.. (2006) Abatacept.. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, [PMID:16573350]
15. Muzny, Donna M DM and 113 more authors.. (2006) The DNA sequence, annotation and analysis of human chromosome 3.. Nature, (27): [PMID:16641997]
16. Weyand, Cornelia M CM and Goronzy, Jörg J JJ.. (2006) T-cell-targeted therapies in rheumatoid arthritis.. Nature clinical practice. Rheumatology, [PMID:16932686]
17. and Scheinfeld, Noah N.. (2006) Abatacept: A review of a new biologic agent for refractory rheumatoid arthritis for dermatologists.. The Journal of dermatological treatment, [PMID:16971318]
18. Vincenti, Flavio F and Luggen, Michael M.. (2007) T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation.. Annual review of medicine, [PMID:17020493]
19. Nogid, Anna A and Pham, David Q DQ.. (2006) Role of abatacept in the management of rheumatoid arthritis.. Clinical therapeutics, [PMID:17212998]
20. Reynolds, Jennifer J, Shojania, Kam K and Marra, Carlo A CA.. (2007) Abatacept: a novel treatment for moderate-to-severe rheumatoid arthritis.. Pharmacotherapy, [PMID:18041889]
21. and Vincenti, Flavio F.. (2008) Costimulation blockade in autoimmunity and transplantation.. The Journal of allergy and clinical immunology, [PMID:18269922]
22. Maxwell, Lara J LJ and Singh, Jasvinder A JA.. (2010) Abatacept for rheumatoid arthritis: a Cochrane systematic review.. The Journal of rheumatology, [PMID:20080922]
23. Kleinpeter, Patricia and 20 more authors.. (2019) By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1.. Journal of virology, (1): [PMID:30918073]

溶液计算器

摩尔浓度计算器

计算溶液所需的质量、体积或浓度。

质量

浓度

体积

分子量

g/mol

稀释计算器

计算配制储备溶液所需的稀释度。

浓度1（C1）

体积 1 (V1)

浓度 2 (C2)

体积 2 (V2)

复溶计算器

复溶计算器允许您快速计算试剂的体积，以复溶小瓶。只需输入试剂的质量和目标浓度，计算器将确定其余部分。

体积（添加到小瓶中）

质量（小瓶）

所需的复溶浓度

CD86 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器

CD86 Mouse mAb

库存信息

库存信息

库存信息

库存信息

基本信息

产品属性

关联靶点（人）

作用机制

图片

应用

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

相关产品

可替换产品

引用文献

溶液计算器

摩尔浓度计算器

稀释计算器

复溶计算器