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CD35 Mouse mAb

    应用:
  • Flow Cytometry
  • 宿主种属: 小鼠(Mouse)
  • 种属反应性: 人(Human)
  • 亚型: Mouse IgG1
  • 克隆号: E11
  • 偶联: Unconjugated
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货号 (SKU) 包装规格 是否现货 价格 数量
Ab006580-10μg
10μg 现货 Stock Image
Ab006580-50μg
50μg 现货 Stock Image
Ab006580-100μg
100μg 现货 Stock Image
Ab006580-1mg
1mg 期货 Stock Image

基本信息

产品名称 CD35 Mouse mAb
别名 Ⅰ型补体受体(C3b/C4b受体)单克隆抗体 | CD35单克隆抗体 | Anti-CD35抗体 | CD35抗体 | CD35单抗 | CD35小鼠单克隆抗体 | CD35小鼠单抗
英文别名 C3BR | CD35 | complement component (3b/4b) receptor 1 (Knops blood group) | CR1 | KN | C3 binding protein antibody | C3b/C4b receptor antibody | C3BR antibody | C4BR antibody | CD 35 antibody | CD35 antibody | CD35 antigen antibody | complement component
规格或纯度 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
宿主种属 小鼠(Mouse)
特异性 CD35
种属反应性 人(Human)
免疫原 Human CD35 from Acute monocytic leukemia cells and normal blood monocytes.
阳性对照 Flow: Human peripheral blood lymphocytes.
偶联 Unconjugated

产品属性

克隆类型 单克隆抗体
克隆号 E11
Format Whole IgG
亚型 Mouse IgG1
SDS-PAGE 150 kDa
纯化方法 Protein G purified
物理外观 Liquid
储存缓冲液 10mM PBS, pH 7.2-7.4
防腐剂 No
浓度 见COA
储存温度 2-8°C储存
运输条件 冰袋运输
稳定性与储存 4°C 下运输。4°C 长期保存(12 个月)。收货后建议分装。
分子类型 抗体

关联靶点(人)

CR1 Tbio 补体受体 1 型(Complement receptor type 1) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

图片

CD35 Mouse mAb (Ab006580) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD35 (red) with CD35 Mouse mAb (Ab006580) at 5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

CD35 Mouse mAb (Ab006580) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD35 with CD35 Mouse mAb (Ab006580) conjugated with biotin (right panel) at 0.02 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

CD35 Mouse mAb (Ab006580) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD35 (red) with CD35 Mouse mAb (Ab006580) conjugated with biotin at 0.02 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称 稀释比例
Flow Cytometry

0.25μg/100w cells

质检证书(CoA,COO,BSE/TSE 和分析图谱)

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找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0505391 分析证书 Ab006580
ZJ24F0505392 分析证书 Ab006580
ZJ24F0505393 分析证书 Ab006580

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引用文献

1. Yaskanin, D D DD, Thompson, L F LF and Waxman, F J FJ..  (1992)  Distribution and quantitative expression of the complement receptor type 1 (CR1) on human peripheral blood T lymphocytes..  Cellular immunology,  [PMID:1534036]
2. Wong, W W WW and 8 more authors..  (1989)  Structure of the human CR1 gene. Molecular basis of the structural and quantitative polymorphisms and identification of a new CR1-like allele..  The Journal of experimental medicine,  (1): [PMID:2564414]
3. Wong, W W WW, Klickstein, L B LB, Smith, J A JA, Weis, J H JH and Fearon, D T DT..  (1985)  Identification of a partial cDNA clone for the human receptor for complement fragments C3b/C4b..  Proceedings of the National Academy of Sciences of the United States of America,  [PMID:2933745]
4. Klickstein, L B LB and 5 more authors..  (1987)  Human C3b/C4b receptor (CR1). Demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristics of C3/C4 binding proteins..  The Journal of experimental medicine,  (1): [PMID:2951479]
5. Hourcade, D D, Miesner, D R DR, Atkinson, J P JP and Holers, V M VM..  (1988)  Identification of an alternative polyadenylation site in the human C3b/C4b receptor (complement receptor type 1) transcriptional unit and prediction of a secreted form of complement receptor type 1..  The Journal of experimental medicine,  (1): [PMID:2971757]
6. Klickstein, L B LB and 5 more authors..  (1988)  Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis..  The Journal of experimental medicine,  (1): [PMID:2972794]
7. Takemura, S S and 7 more authors..  (1984)  C3b receptor (CR1) on erythrocytes in various diseases..  Immunology letters,  [PMID:6233222]
8. Vik, D P DP and Wong, W W WW..  (1993)  Structure of the gene for the F allele of complement receptor type 1 and sequence of the coding region unique to the S allele..  Journal of immunology (Baltimore, Md. : 1950),  (1): [PMID:8245463]
9. Moulds, J M JM, Reveille, J D JD and Arnett, F C FC..  (1996)  Structural polymorphisms of complement receptor 1 (CR1) in systemic lupus erythematosus (SLE) patients and normal controls of three ethnic groups..  Clinical and experimental immunology,  [PMID:8706338]
10. Moulds, J M JM and 14 more authors..  (2001)  Molecular identification of Knops blood group polymorphisms found in long homologous region D of complement receptor 1..  Blood,  (1): [PMID:11313284]
11. Moulds, J M JM and 7 more authors..  (2002)  Expansion of the Knops blood group system and subdivision of Sl(a)..  Transfusion,  [PMID:11896343]
12. Cockburn, Ian A IA and 8 more authors..  (2004)  A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria..  Proceedings of the National Academy of Sciences of the United States of America,  (6): [PMID:14694201]
13. Gregory, S G SG and 178 more authors..  (2006)  The DNA sequence and biological annotation of human chromosome 1..  Nature,  (18): [PMID:16710414]
14. Ogembo, Javier G JG and 6 more authors..  (2013)  Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor..  Cell reports,  (21): [PMID:23416052]
15. Török, Katalin K, Dezső, Balázs B, Bencsik, András A, Uzonyi, Barbara B and Erdei, Anna A..  (2015)  Complement receptor type 1 (CR1/CD35) expressed on activated human CD4+ T cells contributes to generation of regulatory T cells..  Immunology letters,  [PMID:25742728]

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