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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| Ab006580-10μg |
10μg |
现货 ![]() |
| |
| Ab006580-50μg |
50μg |
现货 ![]() |
| |
| Ab006580-100μg |
100μg |
现货 ![]() |
| |
| Ab006580-1mg |
1mg |
期货 ![]() |
|
| 产品名称 | CD35 Mouse mAb |
|---|---|
| 别名 | Ⅰ型补体受体(C3b/C4b受体)单克隆抗体 | CD35单克隆抗体 | Anti-CD35抗体 | CD35抗体 | CD35单抗 | CD35小鼠单克隆抗体 | CD35小鼠单抗 |
| 英文别名 | C3BR | CD35 | complement component (3b/4b) receptor 1 (Knops blood group) | CR1 | KN | C3 binding protein antibody | C3b/C4b receptor antibody | C3BR antibody | C4BR antibody | CD 35 antibody | CD35 antibody | CD35 antigen antibody | complement component |
| 规格或纯度 | 无载体, ExactAb™, 无叠氮钠, 已验证, 见COA |
| 宿主种属 | 小鼠(Mouse) |
| 特异性 | CD35 |
| 种属反应性 | 人(Human) |
| 免疫原 | Human CD35 from Acute monocytic leukemia cells and normal blood monocytes. |
| 阳性对照 | Flow: Human peripheral blood lymphocytes. |
| 偶联 | Unconjugated |
| 克隆类型 | 单克隆抗体 |
|---|---|
| 克隆号 | E11 |
| Format | Whole IgG |
| 亚型 | Mouse IgG1 |
| SDS-PAGE | 150 kDa |
| 纯化方法 | Protein G purified |
| 物理外观 | Liquid |
| 储存缓冲液 | 10mM PBS, pH 7.2-7.4 |
| 防腐剂 | No |
| 浓度 | 见COA |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 稳定性与储存 | 4°C 下运输。4°C 长期保存(12 个月)。收货后建议分装。 |
| 分子类型 | 抗体 |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
CD35 Mouse mAb (Ab006580) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD35 (red) with CD35 Mouse mAb (Ab006580) at 5 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
CD35 Mouse mAb (Ab006580) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD35 with CD35 Mouse mAb (Ab006580) conjugated with biotin (right panel) at 0.02 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
CD35 Mouse mAb (Ab006580) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD35 (red) with CD35 Mouse mAb (Ab006580) conjugated with biotin at 0.02 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
| 应用名称 | 稀释比例 |
|---|---|
| Flow Cytometry | 0.25μg/100w cells |
通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab006580 | |
| 分析证书 | Ab006580 | |
| 分析证书 | Ab006580 |
¥199.90
¥389.90
¥499.90
¥329.90
| 1. Yaskanin, D D DD, Thompson, L F LF and Waxman, F J FJ.. (1992) Distribution and quantitative expression of the complement receptor type 1 (CR1) on human peripheral blood T lymphocytes.. Cellular immunology, [PMID:1534036] |
| 2. Wong, W W WW and 8 more authors.. (1989) Structure of the human CR1 gene. Molecular basis of the structural and quantitative polymorphisms and identification of a new CR1-like allele.. The Journal of experimental medicine, (1): [PMID:2564414] |
| 3. Wong, W W WW, Klickstein, L B LB, Smith, J A JA, Weis, J H JH and Fearon, D T DT.. (1985) Identification of a partial cDNA clone for the human receptor for complement fragments C3b/C4b.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2933745] |
| 4. Klickstein, L B LB and 5 more authors.. (1987) Human C3b/C4b receptor (CR1). Demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristics of C3/C4 binding proteins.. The Journal of experimental medicine, (1): [PMID:2951479] |
| 5. Hourcade, D D, Miesner, D R DR, Atkinson, J P JP and Holers, V M VM.. (1988) Identification of an alternative polyadenylation site in the human C3b/C4b receptor (complement receptor type 1) transcriptional unit and prediction of a secreted form of complement receptor type 1.. The Journal of experimental medicine, (1): [PMID:2971757] |
| 6. Klickstein, L B LB and 5 more authors.. (1988) Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis.. The Journal of experimental medicine, (1): [PMID:2972794] |
| 7. Takemura, S S and 7 more authors.. (1984) C3b receptor (CR1) on erythrocytes in various diseases.. Immunology letters, [PMID:6233222] |
| 8. Vik, D P DP and Wong, W W WW.. (1993) Structure of the gene for the F allele of complement receptor type 1 and sequence of the coding region unique to the S allele.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:8245463] |
| 9. Moulds, J M JM, Reveille, J D JD and Arnett, F C FC.. (1996) Structural polymorphisms of complement receptor 1 (CR1) in systemic lupus erythematosus (SLE) patients and normal controls of three ethnic groups.. Clinical and experimental immunology, [PMID:8706338] |
| 10. Moulds, J M JM and 14 more authors.. (2001) Molecular identification of Knops blood group polymorphisms found in long homologous region D of complement receptor 1.. Blood, (1): [PMID:11313284] |
| 11. Moulds, J M JM and 7 more authors.. (2002) Expansion of the Knops blood group system and subdivision of Sl(a).. Transfusion, [PMID:11896343] |
| 12. Cockburn, Ian A IA and 8 more authors.. (2004) A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria.. Proceedings of the National Academy of Sciences of the United States of America, (6): [PMID:14694201] |
| 13. Gregory, S G SG and 178 more authors.. (2006) The DNA sequence and biological annotation of human chromosome 1.. Nature, (18): [PMID:16710414] |
| 14. Ogembo, Javier G JG and 6 more authors.. (2013) Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor.. Cell reports, (21): [PMID:23416052] |
| 15. Török, Katalin K, Dezső, Balázs B, Bencsik, András A, Uzonyi, Barbara B and Erdei, Anna A.. (2015) Complement receptor type 1 (CR1/CD35) expressed on activated human CD4+ T cells contributes to generation of regulatory T cells.. Immunology letters, [PMID:25742728] |