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Recombinant TCTEX-1 Antibody - Primary antibody, specific to TCTEX-1, Rabbit IgG

    Application:
  • IF/ICC
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab130575
Grouped product items
SKU Size
Availability
Price Qty
Ab130575-10μl
10μl
2
$79.90
Ab130575-50μl
50μl
1
$239.90
Ab130575-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
Ab130575-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Recombinant; Rabbit anti Human TCTEX-1 Antibody; WB, IHC, ICC, IF; Unconjugated

Basic Description

Product Name Recombinant TCTEX-1 Antibody - Primary antibody, specific to TCTEX-1, Rabbit IgG
Synonyms AGS2 antibody | CW 1 antibody | DYLT1_HUMAN antibody | Dynein light chain Tctex-type 1 antibody | DYNLT1 antibody | MGC111571 antibody | Protein CW-1 antibody | RP11-114M11.1 antibody | T complex associated testis expressed 1 like 1 antibody | T-complex t
Specifications & Purity ExactAb™, Validated, Recombinant, 1.5 mg/mL
Host species Rabbit
Specificity TCTEX-1
Immunogen Recombinant protein of human TCTEX-1 (AA 1-113)
Positive Control WB: HeLa, A549, Hep G2, MCF7, NIH/3T3 and C6 cell lysates. IHC: Human tonsil tissue. ICC/IF: HeLa cells.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human TCTEX-1 Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/200
Protein Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein. Plays a role in neuronal morhpogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 1.5 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

DYNLT1 Tbio Dynein light chain Tctex-type 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant TCTEX-1 Antibody (Ab130575) - Western Blot
All lanes: Recombinant TCTEX-1 Antibody (Ab130575) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 12 kDa
Observed band size: 14 kDa
Exposure time: 2.8 s

Recombinant TCTEX-1 Antibody (Ab130575) - IF/ICC
Immunocytochemistry analysis of TCTEX-1 (green) in HeLa using Recombinant TCTEX-1 Antibody (Ab130575) and DAPI (blue).

Recombinant TCTEX-1 Antibody (Ab130575) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil using Recombinant TCTEX-1 Antibody (Ab130575). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
WB

1/500-1/1000

IF/ICC

1/50-1/200

IHC

1/50 - 1/100

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0607291 Certificate of Analysis Jun 24, 2024 Ab130575
ZJ24F0607290 Certificate of Analysis Jun 24, 2024 Ab130575

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