This is a demo store. No orders will be fulfilled.

Recombinant PRMT1 Antibody - Primary antibody, specific to PRMT1, Rabbit IgG

    Application:
  • IHC
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab123096
Grouped product items
SKU Size
Availability
Price Qty
Ab123096-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab123096-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab123096-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab123096-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Recombinant; Rabbit anti Human PRMT1 Antibody; WB, IHC; Unconjugated

Basic Description

Product Name Recombinant PRMT1 Antibody - Primary antibody, specific to PRMT1, Rabbit IgG
Synonyms PRMT1 | ANM1 | HCP1 | IR1B4 | HRMT1L2 | EC 2.1.1 | EC 2.1.1.- | EC 2.1.1.125 | EC 2.1.1.77 | Histone-arginine N-methyltransferase PRMT1 | HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2 | HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae) | HMT1 | H
Specifications & Purity ExactAb™, Validated, Recombinant, 0.5 mg/mL
Host species Rabbit
Specificity PRMT1
Immunogen A synthetic peptide derived from human PRMT1 (AA 327-340)
Positive Control WB: K562, HeLa, HEK293, A549, NIH/3T3 and C6 cell lysates. IHC: Human breast cancer tissue.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human PRMT1 Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function:
Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen Affinity Purified
Shape Liquid
Concentration 0.5 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PRMT1 Tchem Protein arginine N-methyltransferase 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Recombinant PRMT1 Antibody (Ab123096) - Western Blot
All lanes: Recombinant PRMT1 Antibody (Ab123096) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 42 kDa
Observed band size: 37, 41 kDa
Exposure time: 9.4 s

Recombinant PRMT1 Antibody (Ab123096) - IHC
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant PRMT1 Antibody (Ab123096). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Application

Application Dilution info
IHC

1/50 - 1/100

WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0809202 Certificate of Analysis Aug 05, 2024 Ab123096
ZJ24F0809201 Certificate of Analysis Aug 05, 2024 Ab123096

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.