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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab121009-10μl
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10μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$69.90
|
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Ab121009-50μl
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50μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$189.90
|
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Ab121009-100μl
|
100μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$309.90
|
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Ab121009-1ml
|
1ml |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,699.90
|
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Recombinant; Rabbit anti Human PD-L1 Antibody; WB, IHC; Unconjugated
| Product Name | Recombinant PD-L1 Antibody - Primary antibody, specific to CD274, Rabbit IgG | |||||
|---|---|---|---|---|---|---|
| Synonyms | RGD1566211 antibody | Programmed death ligand 1 antibody | Programmed cell death 1 ligand 1 antibody | PDL1 antibody | PDL 1 antibody | PDCD1LG1 antibody | PDCD1L1 antibody | PDCD1 ligand 1 antibody | PD1L1_HUMAN antibody | PD-L1 antibody | PD L1 antibody | |||||
| Specifications & Purity | Recombinant, ExactAb™, Validated, See COA | |||||
| Biochemical and Physiological Mechanisms | Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. | |||||
| Host species | Rabbit | |||||
| Specificity | CD274 | |||||
| Immunogen | A synthetic peptide derived from human PD L1 (AA 200-290). | |||||
| Positive Control | WB: Mouse spleen, Ramos, THP-1, A375, MDA-MB-231 and C6 lysates. IHC: Human thymoma tissue. | |||||
| Conjugation | Unconjugated | |||||
| Grade | ExactAb™, Recombinant, Validated | |||||
| Product Description |
|
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Recombinant PD-L1 Antibody (Ab121009) - Western Blot
All lanes: Recombinant PD-L1 Antibody (Ab121009) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 33 kDa
Observed band size: 41 kDa
Exposure time: 19.5 s
Recombinant PD-L1 Antibody (Ab121009) - Western Blot
All lanes: Recombinant PD-L1 Antibody (Ab121009) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 33 kDa
Observed band size: 41 kDa
Exposure time: 56.5 s
Recombinant PD-L1 Antibody (Ab121009) - IHC
Immunohistochemistry analysis of paraffin-embedded human thymoma tissue labelling PD-L1 with Recombinant PD-L1 Antibody (Ab121009) at 1/100 dilution.
| Application | Dilution info |
|---|---|
| WB | 1/1000 - 1/2000 |
| IHC | 1/100-1/200 |