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Recombinant NF2/Merlin Antibody - Primary antibody, specific to NF2 / Merlin, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab117821
Grouped product items
SKU Size
Availability
Price Qty
Ab117821-10μl
10μl
2
$66.90
Ab117821-50μl
50μl
1
$199.90
Ab117821-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab117821-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human NF2/Merlin Antibody; WB; Unconjugated

Basic Description

Product Name Recombinant NF2/Merlin Antibody - Primary antibody, specific to NF2 / Merlin, Rabbit IgG
Synonyms ACN antibody | BANF antibody | Bilateral acoustic neuroma antibody | MERL_HUMAN antibody | Merlin antibody | Moesin ezrin radixin like protein antibody | Moesin ezrin radizin like antibody | Moesin-ezrin-radixin-like protein antibody | Neurofibromatosis 2
Specifications & Purity ExactAb™, Validated, Recombinant, 1.0 mg/mL
Host species Rabbit
Specificity NF2 / Merlin
Immunogen A synthetic peptide derived from human NF2/Merlin (AA 582-595).
Positive Control WB: Mouse brain tissue lysate; HeLa, Hep G2, Jurkat, MCF7, HUVEC, NIH/3T3 and C6 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human NF2/Merlin Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Antigen affinity purified
Shape Liquid
Concentration 1.0 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

NF2 Tbio Merlin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant NF2/Merlin Antibody (Ab117821) - Western Blot
All lanes: Recombinant NF2/Merlin Antibody (Ab117821) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 70 kDa
Observed band size: 72 kDa
Exposure time: 13.9 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0102620 Certificate of Analysis Jan 30, 2024 Ab117821
ZJ24F0102619 Certificate of Analysis Jan 30, 2024 Ab117821

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