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Recombinant NEDD4-2 Antibody - Primary antibody, specific to NEDD4L, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab117486
Grouped product items
SKU Size
Availability
Price Qty
Ab117486-10μl
10μl
1
$69.90
Ab117486-50μl
50μl
1
$189.90
Ab117486-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$289.90
Ab117486-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human NEDD4-2 Antibody; WB; Unconjugated

Basic Description

Product Name Recombinant NEDD4-2 Antibody - Primary antibody, specific to NEDD4L, Rabbit IgG
Synonyms RSP5 | PVNH7 | NEDD4-2 | NEDD4.2 | hNEDD4-2 | E3 ubiquitin protein ligase NEDD4 like protein antibody | E3 ubiquitin-protein ligase NEDD4-like antibody | KIAA0439 antibody | NEDD4L | NED4L_HUMAN antibody | NEDD4 2 antibody | NEDD4 2c antibody | Nedd4-2 an
Specifications & Purity Recombinant, ExactAb™, Validated, High Performance, See COA
Host species Rabbit
Specificity NEDD4L
Immunogen A synthetic peptide derived from human NEDD4-2 (AA 920-975)
Positive Control WB: K562, HeLa, Jurkat, HEK293, NIH/3T3 and C6 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, High Performance, Recombinant, Validated
Product Description

Rabbit anti Human NEDD4-2 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/5000-1/20000
Protein Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

NEDD4L Tbio E3 ubiquitin-protein ligase NEDD4-like (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant NEDD4-2 Antibody (Ab117486) - Western Blot
All lanes: Recombinant NEDD4-2 Antibody (Ab117486) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/10000 dilution

Predicted band size: 112 kDa
Observed band size: 120 kDa
Exposure time: 104.0 s

Application

Application Dilution info
WB

1/5000-1/20000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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