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Recombinant ApoER2 Antibody - Primary antibody, specific to ApoER2, Rabbit IgG

COA COA
    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab089253
Grouped product items
SKU Size
Availability
 Price Qty
Ab089253-10μl
10μl
2
$69.90
Ab089253-50μl
50μl
1
$199.90
Ab089253-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$319.90
Ab089253-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,099.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Recombinant; Rabbit anti Human ApoER2 Antibody; WB; Unconjugated

View related series
Click to view target information: LRP8
Accession#: Q14114 (1) APOER2 (1) Gene ID: 7804 (1) LRP8 (1)

Basic Description

Product Name Recombinant ApoER2 Antibody - Primary antibody, specific to ApoER2, Rabbit IgG
Synonyms APOER2 antibody | Apolipoprotein E receptor 2 antibody | low density lipoprotein receptor-related protein 8 antibody | Low-density lipoprotein receptor-related protein 8 antibody | LRP-8 antibody | LRP8 antibody | LRP8_HUMAN antibody | LRP8 | MCI1 | LRP-8
Specifications & Purity Recombinant, ExactAb™, KD Validation, Validated, See COA
Host species Rabbit
Specificity ApoER2
Immunogen A synthetic peptide derived from human ApoER2 (AA 900-963).
Positive Control WB: SK-N-SH and C6 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, KD Validation, Recombinant, Validated
Product Description

Rabbit anti Human ApoER2 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function:
Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Binds the endoplasmic reticulum resident receptor-associated protein (RAP). Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature. Highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation. May also function as an endocytic receptor.

Product Properties

Isotype Rabbit IgG
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

LRP8 Tbio Low-density lipoprotein receptor-related protein 8 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Recombinant ApoER2 Antibody (Ab089253) - Western Blot
All lanes: Recombinant ApoER2 Antibody (Ab089253) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 106 kDa
Observed band size: 95 kDa
Exposure time: 39.9 s

Application

Application Dilution info
WB

1/500-1/2000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0607503 Certificate of Analysis Jun 27, 2024 Ab089253
ZJ24F0607502 Certificate of Analysis Jun 27, 2024 Ab089253

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