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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170689-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$79.90
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Ab170689-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$357.90
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Ab170689-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$717.90
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Ab170689-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,167.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Omburtamab (anti-CD276) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD276, >95%, high purity, Human IgG1 |
|---|---|
| Synonyms | Anti-B7-H3 / CD276 Reference Antibody (omburtamab) | Omburtamab | 4Ig B7 H3 antibody | 4Ig-B7-H3 antibody | AU016588 antibody | B7 H3 antibody | B7 homolog 3 antibody | B7-H3 antibody | B7H3 antibody | B7RP-2 antibody | CD_antigen=CD276 antibody | CD276 a |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD276 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Omburtamab (anti-CD276) is an anti-CD276 (also known as B7-H3) monoclonal antibody, CD276 is a B7/CD28 immunoglobulin superfamily member expressed among solid human tumours. Omburtamab can bind tumor tissues and be used in various cancers research. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 26.5 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 175.7 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1895083-75-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Omburtamab (anti-CD276) (Ab170689) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD276 with Omburtamab (anti-CD276) (Ab170689) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Omburtamab (anti-CD276) (Ab170689) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD276 (red) with Omburtamab (anti-CD276) (Ab170689) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Omburtamab (anti-CD276) (Ab170689) - SEC
The purity of Omburtamab (anti-CD276) (Ab170689) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 02, 2023 | Ab170689 | |
| Certificate of Analysis | Nov 02, 2023 | Ab170689 |
Starting at $69.90
Starting at $69.90
Starting at $169.90
Starting at $109.90