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Ifinatamab (anti-CD276) - Primary antibody, specific to CD276, Human IgG1-REM

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1-REM
  • Conjugation: Unconjugated
In stock
Item Number
Ab182965
Grouped product items
SKU Size
Availability
Price Qty
Ab182965-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90
Ab182965-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$829.90
Ab182965-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,079.90
Ab182965-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,329.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1-REM; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Ifinatamab (anti-CD276) - Primary antibody, specific to CD276, Human IgG1-REM
Synonyms 4Ig-B7-H3 antibody | AU016588 antibody | B7 H3 antibody | B7 homolog 3 antibody | B7-H3 antibody | B7H3 antibody | B7RP-2 antibody | CD_antigen=CD276 antibody | CD276 antibody | CD276 antigen antibody | CD276 molecule antibody | CD276_HUMAN antibody | Cos
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD276
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Ifinatamab (anti-CD276) is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab (anti-CD276) is a glycoforme α immunomodulateur.

Purity

≥95% (SDS-PAGE&SEC)

Endotoxin Level

≤1.0EU/mg

Product Properties

Isotype Human IgG1-REM
Light Chain Type kappa
SDS-PAGE 146.52 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
CAS 2484870-90-6

Associated Targets(Human)

CD276 Tbio CD276 antigen (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Ifinatamab (anti-CD276) (Ab182965) - Flow Cytometry
Flow Cytometry analysis of JAR cells labelling CD276 (red) with Ifinatamab (anti-CD276) (Ab182965). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Ifinatamab (anti-CD276) (Ab182965) - Flow Cytometry
Flow Cytometry analysis of U-2 OS cells labelling CD276 (red) with Ifinatamab (anti-CD276) (Ab182965). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Ifinatamab (anti-CD276) (Ab182965) - ELISA
Immobilized Recombinant Human CD276 protein (rp143912) at 1.0 μg/mL can bind Ifinatamab (anti-CD276) (Ab182965) with the EC50 of 23.3 ng/mL.

Ifinatamab (anti-CD276) (Ab182965) - SEC
The purity of Ifinatamab (anti-CD276) (Ab182965) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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