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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182965-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$169.90
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Ab182965-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$829.90
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Ab182965-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Ab182965-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$3,329.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1-REM; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Ifinatamab (anti-CD276) - Primary antibody, specific to CD276, Human IgG1-REM |
|---|---|
| Synonyms | 4Ig-B7-H3 antibody | AU016588 antibody | B7 H3 antibody | B7 homolog 3 antibody | B7-H3 antibody | B7H3 antibody | B7RP-2 antibody | CD_antigen=CD276 antibody | CD276 antibody | CD276 antigen antibody | CD276 molecule antibody | CD276_HUMAN antibody | Cos |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD276 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Ifinatamab (anti-CD276) is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab (anti-CD276) is a glycoforme α immunomodulateur. Purity ≥95% (SDS-PAGE&SEC) Endotoxin Level ≤1.0EU/mg |
| Isotype | Human IgG1-REM |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 146.52 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0 |
| CAS | 2484870-90-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Ifinatamab (anti-CD276) (Ab182965) - Flow Cytometry
Flow Cytometry analysis of JAR cells labelling CD276 (red) with Ifinatamab (anti-CD276) (Ab182965). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Ifinatamab (anti-CD276) (Ab182965) - Flow Cytometry
Flow Cytometry analysis of U-2 OS cells labelling CD276 (red) with Ifinatamab (anti-CD276) (Ab182965). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Ifinatamab (anti-CD276) (Ab182965) - ELISA
Immobilized Recombinant Human CD276 protein (rp143912) at 1.0 μg/mL can bind Ifinatamab (anti-CD276) (Ab182965) with the EC50 of 23.3 ng/mL.
Ifinatamab (anti-CD276) (Ab182965) - SEC
The purity of Ifinatamab (anti-CD276) (Ab182965) is more than 95% verified by HPLC.
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