Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab182915-100μg
|
100μg |
10
|
$69.90
|
|
|
Ab182915-1mg
|
1mg |
4
|
$339.90
|
|
|
Ab182915-5mg
|
5mg |
1
|
$779.90
|
|
|
Ab182915-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,249.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Ociperlimab (anti-TIGIT) - Primary antibody, specific to TIGIT, >95% (SDS-PAGE&SEC), high purity, Human IgG1, INHIBITOR of T-cell immunoreceptor with Ig and ITIM domains inhibitor |
|---|---|
| Synonyms | DKFZp667A205 antibody | ENSMUSG00000071552 antibody | FLJ39873 antibody | RGD1563191 antibody | T cell immunoreceptor with Ig and ITIM domains antibody | TIGIT antibody | TIGIT_HUMAN antibody | V-set and immunoglobulin domain containing 9 antibody | V-set |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TIGIT |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of T-cell immunoreceptor with Ig and ITIM domains inhibitor |
| Product Description |
Ociperlimab (anti-TIGIT) is a humanized IgG1 anti-TIGIT antibody. Ociperlimab (anti-TIGIT) binds to the extracellular domain of human TIGIT with high affinity (KD = 0.135 nM). Ociperlimab (anti-TIGIT) blocks the interaction between TIGIT and its ligands PVR or PVR-L2. Ociperlimab (anti-TIGIT) can be used in research of cancer. Purity >95% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.4 kDa (Light Chain) & 52.2 kDa (Heavy Chain), under reducing conditions; 187.7 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% (SDS-PAGE&SEC) |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2342597-93-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Ociperlimab (anti-TIGIT) (Ab182915) - ELISA
Immobilized Recombinant Human TIGIT Protein (rp152378) at 1.0 μg/mL can bind Ociperlimab (anti-TIGIT) (Ab182915) with the EC₅₀ of 120.2 ng/mL.
Ociperlimab (anti-TIGIT) (Ab182915) - SEC
The purity of Ociperlimab (anti-TIGIT) (Ab182915) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 15, 2024 | Ab182915 | |
| Certificate of Analysis | May 15, 2024 | Ab182915 | |
| Certificate of Analysis | May 15, 2024 | Ab182915 |