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Vibostolimab (anti-TIGIT) - Primary antibody, for Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) various applications, specific to TIGIT, >95%, high purity, Human IgG1, ANTAGONIST of T-cell immunoreceptor with Ig and ITIM domains antagonist, ANTAGONIST of T-cell immunoreceptor with Ig and ITIM domains antagonist

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab169311
Grouped product items
SKU Size
Availability
Price Qty
Ab169311-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab169311-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$297.90
Ab169311-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$717.90
Ab169311-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,137.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Vibostolimab (anti-TIGIT) - Primary antibody, for Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) various applications, specific to TIGIT, >95%, high purity, Human IgG1, ANTAGONIST of T-cell immunoreceptor with Ig and ITIM domains antagonist
Synonyms MK-7684 | Vibostolimab | DKFZp667A205 antibody | ENSMUSG00000071552 antibody | FLJ39873 antibody | RGD1563191 antibody | T cell immunoreceptor with Ig and ITIM domains antibody | TIGIT antibody | TIGIT_HUMAN antibody | V-set and immunoglobulin domain cont
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TIGIT
Application Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action ANTAGONIST of T-cell immunoreceptor with Ig and ITIM domains antagonist
Product Description

Vibostolimab is an anti-TIGIT monoclonal antibody. It shows antitumor activity, and can be used in non-small cell lung cancer (NSCLC) and melanoma research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.2 kDa (Light Chain) & 52.8 kDa (Heavy Chain), under reducing conditions; 181.7 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2231305-30-7

Associated Targets(Human)

TIGIT Tbio T-cell immunoreceptor with Ig and ITIM domains (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Vibostolimab (anti-TIGIT) (Ab169311) - ELISA
Immobilized Human-TIGIT-ECD-his at 2 μg/mL can bind Vibostolimab (anti-TIGIT) (Ab169311) with the EC₅₀ of 18.61 ng/mL.

Vibostolimab (anti-TIGIT) (Ab169311) - SEC
The purity of Vibostolimab (anti-TIGIT) (Ab169311) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001447 Certificate of Analysis Oct 26, 2023 Ab169311
ZJ23F1001448 Certificate of Analysis Oct 26, 2023 Ab169311

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