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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab169311-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab169311-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$297.90
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Ab169311-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$717.90
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Ab169311-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,137.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Vibostolimab (anti-TIGIT) - Primary antibody, for Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) various applications, specific to TIGIT, >95%, high purity, Human IgG1, ANTAGONIST of T-cell immunoreceptor with Ig and ITIM domains antagonist |
|---|---|
| Synonyms | MK-7684 | Vibostolimab | DKFZp667A205 antibody | ENSMUSG00000071552 antibody | FLJ39873 antibody | RGD1563191 antibody | T cell immunoreceptor with Ig and ITIM domains antibody | TIGIT antibody | TIGIT_HUMAN antibody | V-set and immunoglobulin domain cont |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TIGIT |
| Application | Flow,ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTAGONIST |
| Mechanism of action | ANTAGONIST of T-cell immunoreceptor with Ig and ITIM domains antagonist |
| Product Description |
Vibostolimab is an anti-TIGIT monoclonal antibody. It shows antitumor activity, and can be used in non-small cell lung cancer (NSCLC) and melanoma research. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 27.2 kDa (Light Chain) & 52.8 kDa (Heavy Chain), under reducing conditions; 181.7 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2231305-30-7 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Vibostolimab (anti-TIGIT) (Ab169311) - ELISA
Immobilized Human-TIGIT-ECD-his at 2 μg/mL can bind Vibostolimab (anti-TIGIT) (Ab169311) with the EC₅₀ of 18.61 ng/mL.
Vibostolimab (anti-TIGIT) (Ab169311) - SEC
The purity of Vibostolimab (anti-TIGIT) (Ab169311) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Oct 26, 2023 | Ab169311 | |
| Certificate of Analysis | Oct 26, 2023 | Ab169311 |