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Langerin Antibody - Primary antibody, specific to CD207, Rabbit IgG

    Application:
  • WB
  • Host species: Rabbit
  • Reactive species: Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
In stock
Item Number
Ab112769
Grouped product items
SKU Size
Availability
Price Qty
Ab112769-10μl
10μl
2
$79.90
Ab112769-50μl
50μl
1
$229.90
Ab112769-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$339.90
Ab112769-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

pAb; Rabbit anti Human Langerin Antibody; WB; Unconjugated

Basic Description

Product Name Langerin Antibody - Primary antibody, specific to CD207, Rabbit IgG
Synonyms C type lectin domain family 4 member K antibody | C-type lectin domain family 4 member K antibody | CD 207 antibody | CD207 antibody | CD207 antigen antibody | CD207 antigen, langerin antibody | CD207 molecule antibody | CLC4K_HUMAN antibody | CLEC 4K ant
Specifications & Purity Validated, 1.0 mg/mL
Host species Rabbit
Specificity CD207
Immunogen A synthetic peptide derived from human CD207 (AA 61-110).
Positive Control WB: K562, A549, Jurkat, NIH/3T3 and C6 cell lysates.
Conjugation Unconjugated
Grade Validated
Product Description

Rabbit anti Human Langerin Antibody, Polyclonal, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Product Properties

Isotype Rabbit IgG
SDS-PAGE 150 kDa
Purification Method Immunogen affinity purified
Shape Liquid
Concentration 1.0 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CD207 Tbio C-type lectin domain family 4 member K (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Langerin Antibody (Ab112769) - Western Blot
All lanes: Langerin Antibody (Ab112769) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 37 kDa
Observed band size: 37 kDa
Exposure time: 5.1 s

Application

Application Dilution info
WB

1/500-1/2000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0708203 Certificate of Analysis Jul 12, 2024 Ab112769
ZJ24F0708202 Certificate of Analysis Jul 12, 2024 Ab112769

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