This is a demo store. No orders will be fulfilled.

 
Call +1 (833) 552-7181 or Contact us
Toggle Nav
My Cart
Search
Advanced Search
Menu
Account
Settings
྾
main product photo

Cetuximab (anti-EGFR) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ERBB1/EGFR/HER1, >95%, high purity, Human IgG1, Antibody of epidermal growth factor receptor, Antibody of epidermal growth factor receptor

1 Citations COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
C411992
Grouped product items
SKU Size
Availability
 Price Qty
C411992-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
C411992-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$237.90
C411992-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$597.90
C411992-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$867.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: EGFR
Accession#:P00533 (37) EGFR (254) epidermal growth factor receptor Antibody (5) Gene ID:1956 (38) JAK/STAT Signaling (507) m-PEG (327) Protein Tyrosine Kinase/RTK (1314) Receptor Tyrosine Kinase (1260)

Basic Description

Product Name Cetuximab (anti-EGFR) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to ERBB1/EGFR/HER1, >95%, high purity, Human IgG1, Antibody of epidermal growth factor receptor
Synonyms C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference Antibody (cetuximab) | Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin,
Host species Human
Specificity ERBB1/EGFR/HER1
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action Antibody of epidermal growth factor receptor
Product Description

Cetuximab (anti-EGFR) is a human IgG1 monoclonal antibody that inhibits epidermal growth factor receptor (EGFR). Cetuximab (anti-EGFR) has potent antitumor activity. 

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 28.4 kDa (Light Chain) & 53.4 kDa (Heavy Chain), under reducing conditions; 184.2 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 205923-56-4

Associated Targets(Human)

EGFR Tclin Epidermal growth factor receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EGFR Tclin MER intracellular domain/EGFR extracellular domain chimera (2 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EGFR Tclin Protein cereblon/Epidermal growth factor receptor (191 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EGFR Tclin EGFR/PPP1CA (1 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EGFR Tclin VHL/EGFR (323 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Cetuximab (anti-EGFR) (C411992) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling EGFR (red) with Cetuximab (anti-EGFR) (C411992). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Cetuximab (anti-EGFR) (C411992) - SEC
The purity of Cetuximab (anti-EGFR) (C411992) is more than 95% verified by HPLC.

Cetuximab (anti-EGFR) (C411992) - ELISA
Immobilized Human EGFR-Fc at 2 μg/mL can bind Cetuximab (anti-EGFR) (C411992) with the EC₅₀ of 10.67 ng/mL.

Cetuximab (anti-EGFR) (C411992) - ELISA
Immobilized Recombinant Human EGFR protein (rp176273) at 1.0 μg/mL can bind Cetuximab (anti-EGFR) (C411992) with the EC50 of 17.44 ng/mL.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number Certificate Type Date Item
ZJ25F0521992 Certificate of Analysis May 29, 2025 C411992
ZJ25F0521991 Certificate of Analysis May 29, 2025 C411992
ZJ23F0901157 Certificate of Analysis Sep 28, 2023 C411992
ZJ23F0901156 Certificate of Analysis Sep 28, 2023 C411992

Related Products

  1. Human IgG1-kappa (Biotin), anti-Spike RBD
    Human IgG1-kappa (Biotin), anti-Spike RBD

    Starting at $19.90

    Wish List Compare
  2. Goat Anti-Human IgG Fc (AF647)
    Goat Anti-Human IgG Fc (AF647)

    Starting at $10.90

    Wish List Compare
  3. Human IgG (Biotin)
    Human IgG (Biotin)

    Starting at $29.90

    Wish List Compare
  4. Human IgG1(N297S)-kappa, anti-HEL
    Human IgG1(N297S)-kappa, anti-HEL

    Starting at $399.90

    Wish List Compare
  5. Human IgG (AF405)
    Human IgG (AF405)

    Starting at $39.90

    Wish List Compare
  6. Goat Anti-Human IgG Fc (Biotin)
    Goat Anti-Human IgG Fc (Biotin)

    Starting at $10.90

    Wish List Compare
  7. Human IgG (FITC)
    Human IgG (FITC)

    Starting at $19.90

    Wish List Compare
  8. Human IgG1-kappa (AF700), anti-Spike RBD
    Human IgG1-kappa (AF700), anti-Spike RBD

    Starting at $59.90

    Wish List Compare
  9. Human IgG (APC)
    Human IgG (APC)

    Starting at $39.90

    Wish List Compare
  10. Human IgG1(N297Q)-kappa, anti-HEL
    Human IgG1(N297Q)-kappa, anti-HEL

    Starting at $399.90

    Wish List Compare
  11. Goat Anti-Human IgG (FITC)
    Goat Anti-Human IgG (FITC)

    Starting at $19.90

    Wish List Compare
  12. Mouse Anti-Human IgA H&L Antibody
    Mouse Anti-Human IgA H&L Antibody

    Starting at $87.90

    Wish List Compare
  13. Mouse Anti-Human IgE epsilon chain Antibody
    Mouse Anti-Human IgE epsilon chain Antibody

    Starting at $59.90

    Wish List Compare
  14. Goat Anti-Human IgG (AF405)
    Goat Anti-Human IgG (AF405)

    Starting at $19.90

    Wish List Compare
  15. Goat Anti-Human IgG (HRP)
    Goat Anti-Human IgG (HRP)

    Starting at $19.90

    Wish List Compare
  16. Goat Anti-Human IgG (AF488)
    Goat Anti-Human IgG (AF488)

    Starting at $10.90

    Wish List Compare
  17. Human IgG1-kappa (APC), anti-Spike RBD
    Human IgG1-kappa (APC), anti-Spike RBD

    Starting at $21.90

    Wish List Compare
  18. Goat Anti-Human IgG Antibody
    Goat Anti-Human IgG Antibody
    • See COA

    Starting at $87.90

    Wish List Compare
  19. Goat Anti-Human IgG Fc Antibody
    Goat Anti-Human IgG Fc Antibody

    Starting at $29.90

    Wish List Compare
  20. Human IgG (AF700)
    Human IgG (AF700)

    Starting at $39.90

    Wish List Compare

Alternative Products

  1. no_selection
    Necitumumab (anti-EGFR), Antibody of epidermal growth factor receptor

    Starting at $59.90

  2. EGFR Mouse mAb
    EGFR Mouse mAb

    Starting at $49.90

  3. Serclutamab (anti-EGFR)
    Serclutamab (anti-EGFR)

    Starting at $89.90

  4. EGFR Mouse mAb (Biotin)
    EGFR Mouse mAb (Biotin)

    Starting at $69.90

  5. Depatuxizumab mafodotin (anti-EGFR), BINDING AGENT of Epidermal growth factor receptor erbB1 binding agent
    Depatuxizumab mafodotin (anti-EGFR), BINDING AGENT of Epidermal growth factor receptor erbB1 binding agent

    Starting at $199.90

  6. Matuzumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor
    Matuzumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor

    Starting at $79.90

  7. Panitumumab (anti-EGFR), Antibody of epidermal growth factor receptor
    Panitumumab (anti-EGFR), Antibody of epidermal growth factor receptor

    Starting at $49.90

  8. Demupitamab (anti-EGFR)
    Demupitamab (anti-EGFR)

    Starting at $109.90

  9. Losatuxizumab (anti-EGFR)
    Losatuxizumab (anti-EGFR)

    Starting at $59.90

  10. Depatuxizumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor
    Depatuxizumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor

    Starting at $99.90

  11. Modotuximab (anti-EGFR), ANTAGONIST of Epidermal growth factor receptor erbB1 antagonist
    Modotuximab (anti-EGFR), ANTAGONIST of Epidermal growth factor receptor erbB1 antagonist

    Starting at $109.90

  12. Recombinant EGFR Antibody (PE)
    Recombinant EGFR Antibody (PE)

    Starting at $59.90

  13. EGFR Mouse mAb
    EGFR Mouse mAb

    Starting at $59.90

  14. Recombinant EGFR Antibody (Biotin)
    Recombinant EGFR Antibody (Biotin)

    Starting at $69.90

  15. Imgatuzumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor
    Imgatuzumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor

    Starting at $109.90

  16. Zalutumumab (anti-EGFR), ANTAGONIST of Epidermal growth factor receptor erbB1 antagonist
    Zalutumumab (anti-EGFR), ANTAGONIST of Epidermal growth factor receptor erbB1 antagonist

    Starting at $0.00

  17. Nimotuzumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor
    Nimotuzumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitor

    Starting at $99.90

  18. Recombinant EGFR Antibody (FITC)
    Recombinant EGFR Antibody (FITC)

    Starting at $59.90

  19. EGFR Mouse mAb (PE)
    EGFR Mouse mAb (PE)

    Starting at $54.90

  20. Recombinant EGFR Antibody (APC)
    Recombinant EGFR Antibody (APC)

    Starting at $69.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Liyin Wang, Milad Ashrafizadeh, Gautam Sethi, Xinjia Zhou.  (2025)  pH-responsive biomimetic zeolitic imidazolate framework-based nanoparticles for co-delivery of cetuximab and siRNA in synergistic therapy of laryngeal squamous cell carcinoma.  Journal of Pharmaceutical Analysis,    (101203). 

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.