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Immune Checkpoints

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  1. Recombinant Human TNF RII/TNFRSF1B Protein
      Species: Human    Accession #: P20333    
      Système d'expression: E. coli    Journée des protéines: N-His & GST    Concentration d'endotoxine: <1.0 EU/mg    
      Bioactivité: The binding activity of TNFRSF1B and TNFa, the EC50 was 0.0470~0.085 μg/ml.     
    Synonymes: CD120b antigen | CD120b | Etanercept | p75 TNF receptor | p75TBPII | p75TNFR | soluble TNFR1B variant 1 | TNF RII | T...
  2. Recombinant Human 4-1BB Ligand Protein
      Species: Human    Accession #: P41273    
      Système d'expression: E. coli    Journée des protéines: No tag     Concentration d'endotoxine: <1.0 EU/μg    
      Bioactivité: Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.    
    Synonymes: 41BB Ligand | 4-1BB Ligand | 4-1BBL | 4-1BB-L | CD137L | homolog of mouse 4-1BB-L | receptor 4-1BB ligand | TNFSF9 | ...
  3. Recombinant Human CD80 Protein
      Species: Human    Accession #: P33681    
      Système d'expression: HEK293    Journée des protéines: N-His    Concentration d'endotoxine: <1.0 EU/μg    
      Bioactivité: Measured by its binding activity of recombinant human CD80 and recombinant human CD86. The EC50 for this effect is less than 0.412μg/mL.    
    Synonymes: Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1
  4. Recombinant Human Nectin-3 Protein
      Species: Human    Accession #: Q9NQS3    
      Système d'expression: HEK293    Journée des protéines: C-His    Concentration d'endotoxine: <1.0 EU/μg    
      Bioactivité: Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.    
    Synonymes: CDw113 | Nectin cell adhesion molecule 3 | Poliovirus receptor-related protein 3
  5. Recombinant Human Nectin-2/CD112 Protein
      Species: Human    Accession #: Q92692    
      Système d'expression: HEK293    Journée des protéines: No tag     Concentration d'endotoxine: <1.0 EU/μg    
      Bioactivité: Recombinant Human Nectin-2/CD112 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human DNAM-1/CD226 hFc has been identified as an interactor of Nectin-2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-2 and recombinant DNAM-1/CD226 hFc.    
    Synonymes: CD112 antigen | CD112 | Herpes virus entry mediator B | Herpesvirus entry mediator B | herpesvirus entry protein B | ...
  6. Recombinant Human HVEM/TNFRSF14 Protein
      Species: Human    Accession #: Q92956    
      Système d'expression: Pichia pastoris    Journée des protéines: C-hFc    Concentration d'endotoxine: <0.1 EU/μg    
      Bioactivité: Fully biologically active when compared to standard. The biologically active as determined by its ability to inhibit TNF-beta -mediated cytotoxicity using murine L929 cells.    
    Synonymes: ATAR | CD270 antigen | CD270 | CD40-like protein | Herpes virus entry mediator A | Herpesvirus entry mediator A | Hve...
  7. Recombinant Human CD40 Ligand/TNFSF5 Protein
      Species: Human    Accession #: P29965    
      Système d'expression: E. coli    Journée des protéines: No tag     Concentration d'endotoxine: <1.0 EU/μg    
      Bioactivité: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.    
    Synonymes: CD154 antigen | CD154 | CD40 antigen ligand | CD40 Ligand | CD40L | CD40-L | CD40LG | CD40LIGM | gp39 | hCD40L | HIGM...
  8. Recombinant Human CD30-L Protein
      Species: Human    Accession #: P32971    
      Système d'expression: HEK293    Journée des protéines: N-His    Concentration d'endotoxine: <0.1 EU/μg    
      Bioactivité: Measured by its ability to stimulate IL-6 secretion by HDLM human Hodgkin’s lymphoma cells. The ED50 for this effect is 8-48 ng/mL in the presence of 10 µg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody.    
    Synonymes: CD153 antigen; CD153; CD30 antigen ligand; CD30 Ligand; CD30L; CD30-L; CD30LCD30 ligand; CD30LGMGC138144; TNFSF8; tum...
  9. Recombinant Human B7-H2 Protein
      Species: Human    Accession #: O75144    
      Système d'expression: HEK293    Journée des protéines: C-His    Concentration d'endotoxine: <0.01 EU/μg    
      Bioactivité: Immobilized Human ICOSLG at 1 μg/mL (100 μL/well) can bind Human ICOS/CD278 with a linear range of 2-15 ng/mL.     
    Synonymes: B7H2 | B7-H2 | B7H2B7 homolog 2 | B7-H2B7-related protein 1 | B7RP-1 | B7RP1B7-like protein Gl50 | LICOS | CD275 anti...
  10. Recombinant Human CD276 Protein
      Species: Human    Accession #: Q5ZPR3-2    
      Système d'expression: HEK293    Journée des protéines: C-His    Concentration d'endotoxine: <0.1 EU/μg    
      Bioactivité: 1、Immobilized Recombinant Human CD276 Protein (rp143912) at 0.5 μg/mL can bind Anti Human CD276 Antibody with the EC50 of 10.73 ng/mL. 2、Immobilized Recombinant Human CD276 Protein (rp143912) at 1 μg/mL can bind Anti Human CD276 Antibody with a linear range of 1 - 4 ng/mL (EC50:4.3 ng/mL).    
    Synonymes: B7H3 | B7-H3 | B7H34Ig-B7-H3 | B7-H3B7 homolog 3 | CD276 antigen | CD276 molecule | CD276 | Costimulatory molecule | ...
  11. Recombinant Human CD277/BTN3A1 Protein
      Species: Human    Accession #: O00481    
      Système d'expression: HEK293    Journée des protéines: C-hFc & His    Concentration d'endotoxine: <0.1 EU/μg    
      Bioactivité: Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat. The ED₅₀ for this effect is 20-100 ng/mL.    
    Synonymes: BT3.1 | BTF5 | BTN3A1 | Butyrophilin, Subfamily 3,member A1 | CD277 | DJ45P21.3 (Butyrophilin, subfamily 3, member A1...
  12. Recombinant Human BTLA Protein
      Species: Human    Accession #: Q7Z6A9-2    
      Système d'expression: HEK293    Journée des protéines: C-hFc & His    Concentration d'endotoxine: <0.1 EU/μg    
      Bioactivité: Immobilized Recombinant human BTLA at 3 μg/mL (100 μL/well) can bind Biotinylated Recombinant human HVEM with a linear range of 18-72 ng/mL.    
    Synonymes: B and T lymphocyte associated | B and T lymphocyte attenuator | B- and T-lymphocyte attenuator | B- and T-lymphocyte-...
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