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Immune Checkpoints

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  1. Recombinant Mouse B7-H2 Protein
      Species: Mouse    Accession #: Q9JHJ8    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Measured by its ability to co-stimulate IL-4 secretion by D10.G4.1 mouse helper T cells in the presence of anti-CD3. The ED50 for this effect is 0.3-1.5 μg/mL.    
    Synonyms: B7-H2 | B7H2B7 homolog 2 | B7-H2B7-related protein 1 | B7RP-1 | B7RP1B7-like protein Gl50 | B7RP-1LICOS | CD275 antig...
  2. Recombinant Mouse CD137 Protein
      Species: Mouse    Accession #: Q8R037    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by its ability to block 4-1BBL-induced IL-2 secretion by mouse T cells. The ED50 for this effect is 0.3-1 ug/mL in the presence of 0.4 ug/mL of recombinant mouse 4-1BBL    
    Synonyms: 4-1BB ligand receptor | 41BB | 4-1BB | CD137 antigen | CD137 | CD137MGC2172 | CDw137 | FLJ43501 | ILA | ILAhomolog of...
  3. Recombinant Human CD40 Protein
      Species: Human    Accession #: P25942    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Immobilized human CD40L-His at 10 μg/mL (100 μL/well) can bind Human CD40-Fc. The EC50 of Human CD40-Fc is 10-30 ng/mL.    
    Synonyms: AI326936 | B cell associated molecule CD40 | B cell surface antigen CD40 | B cell-associated molecule | B-cell surfac...
  4. Recombinant Human B7-2/CD86 Protein
      Species: Human    Accession #: P42081-1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Recombinant Human CD86 at 2 μg/mL (100 μL/well) can bind Recombinant Human CTLA-4 with a linear range of 10-40 ng/mL.    
    Synonyms: Activation B7-2 antigen | Activation B7-2 antigen 3 | B-lymphocyte activation antigen B7-2 | B-lymphocyte activation ...
  5. Recombinant Human CD47 Protein
      Species: Human    Accession #: Q08722    
      Expression system: HEK293    Protein Tag: C-hFc    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: 1. Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC50 of human CD47 Protein is 50.0 - 200.0 ng/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD47 Protein (rp144028) at 1 μg/mL can bind Magrolimab (anti-CD47) (Ab169323) with the EC50 of 10.34 ng/mL.    
    Synonyms: antigen identified by monoclonal 1D8 | Antigenic surface determinant protein OA3 | CD47 antigen (Rh-related antigen, ...
  6. Recombinant Human TIM 3 Protein
      Species: Human    Accession #: Q8TDQ0    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Human Galectin-9 at 2 μg/mL can bind recombinant human TIM-3 with a linear range of 0.3 - 5 μg/mL.    
    Synonyms: CD366 | FLJ14428 | HAVCR2 | HAVcr-2 | hepatitis A virus cellular receptor 2 | kidney injury molecule-3 | KIM-3 | SPTC...
  7. Recombinant Human TIGIT Protein
      Species: Human    Accession #: Q495A1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Human TIGIT at 1.5 μg/mL (100 μL/well) can bind Human CD155 with a linear range of 0.15-1.2 μg/mL.    
    Synonyms: T cell immunoreceptor with Ig and ITIM domains | TIGIT | VSIG9 | VSTM3 | WUCAM | V-set and immunoglobulin domain-cont...
  8. Recombinant Human PD-L2/B7-DC Protein
      Species: Human    Accession #: Q9BQ51    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.01 EU/μg    
      Bioactivity: Immobilized Recombinant Human PD-L2 at 5 μg/mL (100 μL/well) can bind Recombinant Human PD-1 with a linear range of 0.2-1.0 μg/mL.    
    Synonyms: B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; Butyrophilin-like Protein; CD273 antigen; CD273; CD273PD-1 ligand 2; MGC...
  9. Recombinant Human Poliovirus Receptor/PVR Protein
      Species: Human    Accession #: P15151-1    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Human TIGIT (rp152378) at 1.5 μg/mL can bind Recombinant Human Poliovirus Receptor/PVR Protein (rp150374) with a linear range of 0.15 - 1.2 μg/mL.    
    Synonyms: CD155 | CD155 antigen | FLJ25946 | HVED | mE4 | NECL 5 | Necl-5 | Necl5 | Nectin like 5 | Nectin like protein 5 | Nec...
  10. Recombinant Human CD40 Ligand/TNFSF5 Protein
      Species: Human    Accession #: P29965    
      Expression system: E. coli    Protein Tag: N-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Testing in progress    
    Synonyms: CD154 antigen | CD154 | CD40 antigen ligand | CD40 Ligand | CD40L | CD40-L | CD40LG | CD40LIGM | gp39 | hCD40L | HIGM...
  11. Recombinant human CD48 protein
      Species: Human    Accession #: P09326-1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured by its ability to bind recombinant human CD244. Immobilized recombinant human CD48 at 5 μg/mL (100 μL/well) can bind recombinant human CD244 with a linear range of 0.2-1 μg/mL.    
    Synonyms: BCM1 surface antigen | BCM1 | BCM1Leukocyte antigen MEM-102 | BLAST | BLAST1 | BLAST1TCT.1 | B-lymphocyte activation ...
  12. Recombinant Human CD96 Protein
      Species: Human    Accession #: P40200-2    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Human CD155/PVR hFc at 2 μg/ml (100 μl/well) can bind Human CD96 His, the EC50 of Human CD96 His is 200-800 ng/mL.    
    Synonyms: CD96 | CD96 molecule | Cell surface antigen CD96 | DKFZp667E2122 | MGC22596 | T cell activated increased late express...
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