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Antibody-Drug Conjugate (ADCs) Discovery
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Recombinant Human CD33 ProteinSpecies: Human Accession #: P20138Expression system: HEK293 Protein Tag: C-hFc & His Endotoxin Concentration: <0.1 EU/μgBioactivity: 1、Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. The ED50 for this effect is 1‑4 µg/mL. 2、Immobilized Recombinant Human CD33 Protein (rp143966) at 2.0 μg/mL can bind Gemtuzumab (anti-CD33) (Ab175859). The ED50 for this effect is 391.3 ng/mL.Synonyms: CD33 antigen (gp67) | CD33 antigen | CD33 molecule | CD33 | FLJ00391 | gp67 | myeloid cell surface antigen CD33 | p67...
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Recombinant Human CD22 ProteinSpecies: Human Accession #: P20273Expression system: HEK293 Protein Tag: C-Fc & His Endotoxin Concentration: <0.1 EU/μgBioactivity: Immobilized Recombinant Human CD22 Protein (rp143882) at 1 μg/mL can bind Recombinant CD22 Antibody (Ab094265) with a EC50 is 4.6 ng/mL.Synonyms: B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22 molecule; CD22; sialic...
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Recombinant Human ErbB2/Her2 ProteinSpecies: Human Accession #: P04626Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <0.1 EU/μgBioactivity: Immobilized recombinant human ERBB2 at 10 ng/mL (100 μL/well) can bind Trastuzumab with a linear range of 4-20 ng/mL.Synonyms: CD340 antigen | CD340 | C-erb B2/neu protein | EC 2.7.10 | EGFR2 | ErbB2 | HER2 | HER-2 | HER2EC 2.7.10.1 | Herstatin...
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Recombinant Human FOLR1 ProteinSpecies: Human Accession #: P15328Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <0.1 EU/μgBioactivity: Immobilized Human FOLR1 at 1 μg/mL (100 μL/well) can bind FOLR1 Antibody with a linear range of 0.2-1 ng/mLSynonyms: adult | Adult folate binding protein | Adult folate-binding protein | FBP | Folate Binding Protein | Folate receptor ...
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Recombinant Human Guanylyl Cyclase C/GC-C ProteinSpecies: Human Accession #: P25092-1Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <0.1 EU/μgBioactivity: Immobilized Human GUCY2C at 1 μg/mL (100 μL/well) can bind GUCY2C antibody with a linear range of 1-144 ng/mL.Synonyms: GC-C | Guanylyl cyclase C | GUC2C | GUC2C_HUMAN | GUCY2C | Heat stable enterotoxin receptor | Heat-stable enterotoxin...
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Recombinant Human CD4 ProteinSpecies: Human Accession #: P01730Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Measured by the ability of the immobilized protein to support the adhesion of HeLa human cervical epithelial carcinoma cells. The ED50 for this effect is 40.0 ng/mL. Measured by its binding ability in a functional ELISA. Immobilized Human CD4 protein (rp175911) at 1.0 μg/mL can bind Ibalizumab (anti-CD4) (Ab170728) with the EC50 of 52.66 ng/mL.Synonyms: CD 4 | CD4 | CD4 (L3T4) | CD4 antigen | CD4 antigen (p55) | CD4 molecule | CD4 receptor | CD4+ Lymphocyte deficiency,...
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Recombinant Human Mesothelin ProteinSpecies: Human Accession #: Q13421Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Measured by its binding ability in a functional ELISA. Human Mesothelin protein (rp176301) at 1 μg/mL can bind Human Osteopontin ( rp149597) with the EC50 of 30.0 ng/mL.Synonyms: CAK 1 | CAK1 | CAK1 antigen | cleaved form | Megakaryocyte potentiating factor | Mesothelin | Mesothelin isoform 1 pr...
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Recombinant Human ROR1 ProteinSpecies: Human Accession #: Q01973Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Immobilized Recombinant Human ROR1 Protein (rp176297) at 2.0 μg/mL can bind Zilovertamab (anti-ROR1) (Ab170644) , the EC50 is 16.07 ng/mL.Synonyms: dJ537F10.1 | Inactive tyrosine protein kinase transmembrane receptor ROR1 | MGC99659 | Neurotrophic tyrosine kinase |...
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Recombinant Human ErbB2/HER2 ProteinSpecies: Human Accession #: P04626Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Pertuzumab (anti-HER2) (P412000) at 1.0 ug/mL can bind biotinylated Human ErbB2/HER2 Protein (rp169607), The EC50 for this effect is 25.99 ng/mL.Synonyms: CD340 antigen | CD340 | c-erb B2/neu protein | EC 2.7.10 | EGFR2 | ErbB2 | HER2 | HER-2 | HER2EC 2.7.10.1 | herstatin...
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Recombinant Feline CD4 ProteinSpecies: Feline Accession #: P79355Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgSynonyms: CD_antigen: CD4 | CD4 antigen (p55) | CD4 antigen | CD4 molecule | CD4 receptor | CD4 | CD4mut | T-cell surface antig...
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Recombinant Canine CD4 ProteinSpecies: Canine Accession #: P33705Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Bioassay data are not available.Synonyms: CD_antigen: CD4 | CD4 antigen (p55) | CD4 antigen | CD4 molecule | CD4 receptor | CD4 | CD4mut | T-cell surface antig...
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Recombinant Bovine CD4 ProteinSpecies: Bovine Accession #: F1MJK4Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Measured by the ability of the immobilized protein to support the adhesion of NIH‑3T3 mouse embryonic fibroblast cells.The ED50for this effect is 0.1-0.5 μg/mL after a 1 hour incubation at37 °C.Optimal dilutions should be determined by each laboratory for each application.Synonyms: T-cell surface glycoprotein CD4 | T-cell surface antigen T4/Leu-3 | CD4
