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PD-L1 Mouse mAb - Primary antibody, specific to PD-L1, Mouse IgG2b

    Application:
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG2b
  • Clone Number: 29E.2A3
  • Conjugation: Unconjugated
In stock
Item Number
Ab121011
Grouped product items
SKU Size
Availability
Price Qty
Ab121011-10μg
10μg
10
$16.90
Ab121011-50μg
50μg
4
$49.90
Ab121011-100μg
100μg
2
$79.90
Ab121011-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$699.90

mAb (29E.2A3); Mouse anti Human PD-L1 Antibody; Flow; Unconjugated

Basic Description

Product Name PD-L1 Mouse mAb - Primary antibody, specific to PD-L1, Mouse IgG2b
Synonyms Avelumab | B7-H | B7H1 | B7-H1 | B7H1PDCD1L1 | CD274 antigenMGC142294 | CD274 molecule | CD274 | PDCD1L1 | PDCD1LG1 | PDCD1LG1MGC142296 | PDL1 | PD-L1 | PD-L1B7 homolog 1 | PDL1PDCD1 ligand 1 | programmed cell death 1 ligand 1 | Programmed death ligand 1
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, See COA
Host species Mouse
Specificity PD-L1
Immunogen Full length human PD-L1
Positive Control Flow: Stimulate human PBMC with PHA
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human PD-L1 Antibody, Monoclonal (29E.2A3), could be used for Flow and so on.
Application:
Flow: 0.06 μg/100w cells
Protein Function
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Product Properties

Isotype Mouse IgG2b
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

CD274 Tclin Programmed cell death 1 ligand 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

PD-L1 Mouse mAb (Ab121011) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-L1 (red) with PD-L1 Mouse mAb (Ab121011) at 0.1 μg/mL for 1 hour at 4°C. Goat anti Mouse IgG H&L(PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow Cytometry

0.06 μg/100w cells

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404688 Certificate of Analysis Apr 19, 2024 Ab121011
ZJ24F0404687 Certificate of Analysis Apr 19, 2024 Ab121011
ZJ24F0404686 Certificate of Analysis Apr 19, 2024 Ab121011

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