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Sugemalimab (anti-PD-L1) - Primary antibody, specific to CD274, >95%, high purity, Human IgG4SP, BINDING AGENT of Programmed cell death 1 ligand 1 binding agent, BINDING AGENT of Programmed cell death 1 ligand 1 binding agent

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab175662
Grouped product items
SKU Size
Availability
 Price Qty
Ab175662-100μg
100μg
10
$149.90
Ab175662-1mg
1mg
4
$709.90
Ab175662-5mg
5mg
1
$1,779.90
Ab175662-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,849.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CD274
Accession#:Q9NZQ7 (26) Gene ID:29126 (26) PD-L1 (22)

Basic Description

Product Name Sugemalimab (anti-PD-L1) - Primary antibody, specific to CD274, >95%, high purity, Human IgG4SP, BINDING AGENT of Programmed cell death 1 ligand 1 binding agent
Synonyms B7 H antibody | B7 H1 antibody | B7 homolog 1 antibody | B7-H1 antibody | B7H antibody | B7H1 antibody | CD 274 antibody | CD-274 antibody | CD274 antibody | CD274 antigen antibody | CD274 molecule antibody | MGC142294 antibody | MGC142296 antibody | OTTH
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD274
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action BINDING AGENT of Programmed cell death 1 ligand 1 binding agent
Product Description

Sugemalimab (anti-PD-L1) is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab (anti-PD-L1) shows anticancer activities and can be used for non-small cell lung cancer research.

Product Properties

Isotype Human IgG4SP
Light Chain Type lambda
SDS-PAGE 27.2 kDa (Light Chain) & 51.2 kDa (Heavy Chain), under reducing conditions; 183.8 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2256084-03-2

Associated Targets(Human)

CD274 Tclin Programmed cell death 1 ligand 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Sugemalimab (anti-PD-L1) (Ab175662) - Flow Cytometry
Flow Cytometry analysis of 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated Jurkat cells (24h) labelling PD-L1 (red) with Sugemalimab (anti-PD-L1) (Ab175662). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Sugemalimab (anti-PD-L1) (Ab175662) - SEC
The purity of Sugemalimab (anti-PD-L1) (Ab175662) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404392 Certificate of Analysis Apr 10, 2024 Ab175662
ZJ24F0404391 Certificate of Analysis Apr 10, 2024 Ab175662
ZJ24F0404390 Certificate of Analysis Apr 10, 2024 Ab175662

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