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Moxetumomab (anti-CD22) - Primary antibody, specific to CD22, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab191901
Grouped product items
SKU Size
Availability
Price Qty
Ab191901-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab191901-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$259.90
Ab191901-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$669.90
Ab191901-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,079.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Moxetumomab (anti-CD22) - Primary antibody, specific to CD22, Human IgG1
Synonyms B cell receptor CD22 precursor antibody | B lymphocyte cell adhesion molecule antibody | B-cell receptor CD22 antibody | B-lymphocyte cell adhesion molecule antibody | BL CAM antibody | BL-CAM antibody | BLCAM antibody | CD 22 antibody | CD22 antibody | C
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be ma
Host species Human
Specificity CD22
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Moxetumomab (anti-CD22), a recombinant CD22-targeting immunotoxin, can be used for the research of hairy cell leukemia (HCL).

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 146.14 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1622075-65-3

Associated Targets(Human)

CD22 Tclin B-cell receptor CD22 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Moxetumomab (anti-CD22) (Ab191901) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD22 (red) with Moxetumomab (anti-CD22) (Ab191901) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Moxetumomab (anti-CD22) (Ab191901) - ELISA
Immobilized Recombinant Human Siglec-2/CD22 protein (rp169575) at 1.0 μg/mL can bind Moxetumomab (anti-CD22) (Ab191901) with the EC50 of 23.33 ng/mL.

Moxetumomab (anti-CD22) (Ab191901) - SEC
The purity of Moxetumomab (anti-CD22) (Ab191901) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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