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Pinatuzumab (anti-CD22) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD22, >95%, high purity, Human IgG1

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170658
Grouped product items
SKU Size
Availability
 Price Qty
Ab170658-100μg
100μg
10
$109.90
Ab170658-1mg
1mg
4
$519.90
Ab170658-5mg
5mg
1
$1,399.90
Ab170658-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CD22
Accession#:P20273 (13) CD22 (15) Gene ID:933 (14) SIGLEC-2 (5)

Basic Description

Product Name Pinatuzumab (anti-CD22) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CD22, >95%, high purity, Human IgG1
Synonyms Anti-Siglec-2 / CD22 Reference Antibody (pinatuzumab) | Pinatuzumab | B cell receptor CD22 precursor antibody | B lymphocyte cell adhesion molecule antibody | B-cell receptor CD22 antibody | B-lymphocyte cell adhesion molecule antibody | BL CAM antibody |
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD22
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Pinatuzumab (anti-CD22) is a CD22 monoclonal antibody. Pinatuzumab targets the cell-surface antigen CD22. Pinatuzumab can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including non-Hodgkin lymphoma (NHL).
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
≤1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 147 kDa
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1639820-81-7

Associated Targets(Human)

CD22 Tclin B-cell receptor CD22 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Pinatuzumab (anti-CD22) (Ab170658) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 with Pinatuzumab (anti-CD22) (Ab170658) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

Pinatuzumab (anti-CD22) (Ab170658) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD22 (red) with Pinatuzumab (anti-CD22) (Ab170658) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Pinatuzumab (anti-CD22) (Ab170658) - Flow Cytometry
Flow Cytometry analysis of Ramos cells labelling CD22 (red) with Pinatuzumab (anti-CD22) (Ab170658). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Pinatuzumab (anti-CD22) (Ab170658) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD22 (red) with Pinatuzumab (anti-CD22) (Ab170658). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Pinatuzumab (anti-CD22) (Ab170658) - ELISA
Immobilized Recombinant Human Siglec-2/CD22 protein (rp169575) at 1.0 μg/mL can bind Pinatuzumab (anti-CD22) (Ab170658) with the EC ₅₀  of 61.07 ng/mL.

Pinatuzumab (anti-CD22) (Ab170658) - SEC
The purity of Pinatuzumab (anti-CD22) (Ab170658) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0606885 Certificate of Analysis Jun 14, 2024 Ab170658
ZJ24F0606884 Certificate of Analysis Jun 14, 2024 Ab170658
ZJ24F0606886 Certificate of Analysis Jun 14, 2024 Ab170658

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