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Avelumab (anti-PD-L1) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to B7-H1 / PD-L1 / CD274, >95%, high purity, Human IgG1, OTHER of Programmed cell death 1 ligand 1 other, OTHER of Programmed cell death 1 ligand 1 other

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Dog,Human,Mouse,Rabbit,Rat
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
A412006
Grouped product items
SKU Size
Availability
 Price Qty
A412006-100μg
100μg
10
$99.90
A412006-1mg
1mg
5
$454.90
A412006-5mg
5mg
1
$1,894.90
A412006-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,410.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CD274
Accession#:Q9NZQ7 (26) Gene ID:29126 (26) Immunology/Inflammation (1929) PD-1/PD-L1 (59) PD-L1 (22)

Basic Description

Product Name Avelumab (anti-PD-L1) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to B7-H1 / PD-L1 / CD274, >95%, high purity, Human IgG1, OTHER of Programmed cell death 1 ligand 1 other
Synonyms Recombinant Avelumab Antibody | Avelumab | Anti-Human PD-L1, Human Antibody | Anti-PD-L1 | MSB0010718C | Bavencio | B7 H antibody | B7 H1 antibody | B7 homolog 1 antibody | B7-H1 antibody | B7H antibody | B7H1 antibody | CD 274 antibody | CD-274 antibody
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity B7-H1 / PD-L1 / CD274
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type OTHER
Mechanism of action OTHER of Programmed cell death 1 ligand 1 other
Product Description

Avelumab is a fully human IgG1 monoclonal antibody that targets the protein programmed death-ligand 1 (PD-L1). Avelumab exhibits potential antibody-dependent cell-mediated cytotoxicity and is used for the treatment of several kinds of carcinoma.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg 

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 28.7 kDa (Light Chain) & 50.1 kDa (Heavy Chain), under reducing conditions; 182.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1537032-82-8

Associated Targets(Human)

CD274 Tclin Programmed cell death 1 ligand 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Avelumab (anti-PD-L1) (A412006) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling PD-L1 with Avelumab (anti-PD-L1) (A412006) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

Avelumab (anti-PD-L1) (A412006) - Flow Cytometry
Flow Cytometry analysis of PHA-stimulated (3 days) human peripheral blood lymphocytes labelling PD-L1 (red) with Avelumab (anti-PD-L1) (A412006) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

Avelumab (anti-PD-L1) (A412006) - SEC
The purity of Avelumab (anti-PD-L1) (A412006) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404943 Certificate of Analysis Apr 26, 2024 A412006
ZJ23F1101612 Certificate of Analysis Nov 08, 2023 A412006
ZJ23F1101613 Certificate of Analysis Nov 08, 2023 A412006

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