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Bococizumab (anti-PCSK9) - Primary antibody, specific to PCSK9, >95%, high purity, Human IgG2, Antibody of proprotein convertase subtilisin/kexin type 9, Antibody of proprotein convertase subtilisin/kexin type 9

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG2
  • Conjugation: Unconjugated
In stock
Item Number
Ab175476
Grouped product items
SKU Size
Availability
 Price Qty
Ab175476-100μg
100μg
10
$79.90
Ab175476-1mg
1mg
4
$399.90
Ab175476-5mg
5mg
1
$999.90
Ab175476-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,599.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: PCSK9
Accession#:Q8NBP7 (13) Gene ID:255738 (13) Lipid metabolism (1912) PCSK9 (13) proprotein convertase subtilisin/kexin type 9 Antibody (6)

Basic Description

Product Name Bococizumab (anti-PCSK9) - Primary antibody, specific to PCSK9, >95%, high purity, Human IgG2, Antibody of proprotein convertase subtilisin/kexin type 9
Synonyms Convertase subtilisin/kexin type 9 preproprotein antibody | FH3 antibody | HCHOLA3 antibody | Hypercholesterolemia autosomal dominant 3 antibody | LDLCQ1 antibody | NARC 1 antibody | NARC-1 antibody | NARC1 antibody | Neural apoptosis regulated convertase
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity PCSK9
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action Antibody of proprotein convertase subtilisin/kexin type 9
Product Description

Bococizumab (anti-PCSK9) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab (anti-PCSK9) can be used in the research of hypercholesterolemia.

Product Properties

Isotype Human IgG2
Light Chain Type kappa
SDS-PAGE 26.6 kDa (Light Chain) & 51.4 kDa (Heavy Chain), under reducing conditions; 180.0kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1407495-02-6

Associated Targets(Human)

PCSK9 Tclin Proprotein convertase subtilisin/kexin type 9 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
PCSK9 Tclin Subtilisin/kexin type 9 (362 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Bococizumab (anti-PCSK9) (Ab175476) - SEC
The purity of Bococizumab (anti-PCSK9) (Ab175476) is more than 95% verified by HPLC.

Bococizumab (anti-PCSK9) (Ab175476) - ELISA
Immobilized hu-PCSK9-chis at 2 μg/mL can bind Bococizumab (anti-PCSK9) (Ab175476) with the EC₅₀ of 6.92 ng/mL.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303753 Certificate of Analysis Mar 29, 2024 Ab175476
ZJ24F0303752 Certificate of Analysis Mar 29, 2024 Ab175476
ZJ24F0303751 Certificate of Analysis Mar 29, 2024 Ab175476

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