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Lodelcizumab (anti-PCSK9) - Primary antibody, specific to PCSK9, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse,Rat
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab190154
Grouped product items
SKU Size
Availability
Price Qty
Ab190154-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab190154-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90
Ab190154-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,299.90
Ab190154-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,079.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Lodelcizumab (anti-PCSK9) - Primary antibody, specific to PCSK9, Human IgG1
Synonyms Convertase subtilisin/kexin type 9 preproprotein antibody | FH3 antibody | HCHOLA3 antibody | Hypercholesterolemia autosomal dominant 3 antibody | LDLCQ1 antibody | NARC 1 antibody | NARC-1 antibody | NARC1 antibody | Neural apoptosis regulated convertase
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis. Post-translational: The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage
Host species Human
Specificity PCSK9
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Lodelcizumab (anti-PCSK9) is a monoclonal antibody. Lodelcizumab (anti-PCSK9) can be used for the research of hypercholesterolemia.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1355338-54-3

Associated Targets(Human)

PCSK9 Tclin Proprotein convertase subtilisin/kexin type 9 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
PCSK9 Tclin Subtilisin/kexin type 9 (362 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Lodelcizumab (anti-PCSK9) (Ab190154) - ELISA
Immobilized Recombinant Human PCSK9 protein (rp170397) at 1.0 μg/mL can bind Lodelcizumab (anti-PCSK9) (Ab190154) with the EC50 of 844.0 ng/mL.

Lodelcizumab (anti-PCSK9) (Ab190154) - SEC
The purity of Lodelcizumab (anti-PCSK9) (Ab190154) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Alternative Products

Solution Calculators

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