基本信息

产品名称	Recombinant CD45.1 Antibody (APC)
别名	白细胞共同抗原 \| 蛋白酪氨酸磷酸酶受体C \| CD45抗体 \| CD45.1抗体 \| CD45.1单克隆抗体 \| Anti-CD45.1抗体
英文别名	B220 antibody \| CD45 antibody \| CD45 antigen antibody \| CD45R antibody \| GP180 antibody \| L-CA antibody \| LCA antibody \| LY5 antibody \| Protein tyrosine phosphatase receptor type C antibody \| Protein tyrosine phosphatase, receptor type, c polypeptide anti
规格或纯度	ExactAb™, 已验证, 0.5 mg/mL
生化机理	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity.
宿主种属	小鼠(Mouse)
特异性	Mouse CD45.1
种属反应性	小鼠(Mouse)
免疫原	SJL mouse thymocytes and splenocytes.
阳性对照	Flow Cytometry: SJL mouse splenocytes.
偶联	APC
Excitation(nm)	Red Laser(633nm)
Emission(nm)	660nm
Ex/Em(nm)	Ex:650nm;Em:660nm

产品属性

克隆类型	重组抗体
Format	Whole IgG
轻链亚型	kappa
纯化方法	Protein A purified
储存缓冲液	Liquid in PBS pH 7.4, containing 1% BSA and 0.05% Proclin300.
防腐剂	0.05% Proclin300
浓度	0.5 mg/mL
储存温度	2-8°C储存,避光,禁止冷冻
运输条件	冰袋运输
稳定性与储存	The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
分子类型	抗体

关联靶点（人）

PTPRC Tchem 受体型酪氨酸蛋白磷酸酶C(Receptor-type tyrosine-protein phosphatase C) (0 活性数据)

点击查看靶蛋白信息： PTPRC

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

图片

Flow Cytometry: Recombinant CD45.1 Antibody (APC) (Ab213891)

Recombinant CD45.1 Antibody (APC) (Ab213891) - Flow Cytometry
Flow cytometry analysis of CD45.1 expression by SJL mouse splenocytes (right panel) compared to an isotype control (left panel). Cells were stained with Recombinant CD45.1 Antibody (APC) (Ab213891) at 0.1μg/test for 1 hour at 4°C. Left panel - Mouse IgG (APC) (Ab180309).

Flow Cytometry: Recombinant CD45.1 Antibody (APC) (Ab213891)

Recombinant CD45.1 Antibody (APC) (Ab213891) - Flow Cytometry
Flow cytometry analysis of CD45.1 expression by SJL mouse splenocytes (red) compared to an isotype control (blue). Cells were stained with Recombinant CD45.1 Antibody (APC) (Ab213891) at 0.1μg/test for 1 hour at 4°C. Blue - Mouse IgG (APC) (Ab180309). Black - Unlabelled control, cells without incubation with primary antibody.

应用

应用名称	稀释比例
Flow Cytometry	≤0.3μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume.