基本信息

产品名称	Budigalimab (anti-PD-1), 程序性细胞死亡蛋白 1 抑制剂
别名	布格利单抗 \| 布迪加单抗（抗 PD-1）
英文别名	CD279 antibody \| CD279 antigen antibody \| hPD 1 antibody \| hPD l antibody \| hPD-1 antibody \| hSLE1 antibody \| PD 1 antibody \| PD-1 antibody \| PD1 antibody \| PDCD 1 antibody \| PDCD1_HUMAN antibody \| PDCD1 antibody \| Programmed cell death 1 antibody \| Progr
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	PDCD1
种属反应性	人(Human),食蟹猴(Cynomolgus monkey)
偶联	Unconjugated
作用类型	抑制剂
作用机制	程序性细胞死亡蛋白 1 抑制剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG1
轻链亚型	kappa
SDS-PAGE	144.76 kDa
纯化方法	Protein A purified
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	2098225-93-3
分子类型	抗体

关联靶点（人）

PDCD1 Tclin 程序性细胞死亡蛋白 1(Programmed cell death protein 1) (0 活性数据)

点击查看靶蛋白信息： PDCD1

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

PDCD1 Tclin Programmed cell death protein 1 (14 活性数据)

点击查看靶蛋白信息： PDCD1

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

图片

Flow Cytometry: Budigalimab (anti-PD-1) (Ab182803)

Budigalimab (anti-PD-1) (Ab182803) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-1 (red) with Budigalimab (anti-PD-1) (Ab182803) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Flow Cytometry: Budigalimab (anti-PD-1) (Ab182803)

Budigalimab (anti-PD-1) (Ab182803) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) MOLT-4 cells labelling PD-1 (red) with Budigalimab (anti-PD-1) (Ab182803) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Budigalimab (anti-PD-1) (Ab182803)

Budigalimab (anti-PD-1) (Ab182803) - ELISA
Immobilized Recombinant Human PD-1 protein (rp176241) at 1.0 μg/mL can bind Budigalimab (anti-PD-1) (Ab182803) with the EC₅₀ of 17.44 ng/mL.

SEC: Budigalimab (anti-PD-1) (Ab182803)

Budigalimab (anti-PD-1) (Ab182803) - SEC
The purity of Budigalimab (anti-PD-1) (Ab182803) is more than 95% verified by HPLC.

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

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找到6个结果

批号(Lot Number)	证书类型	货号
ZJ24F1114117	分析证书	Ab182803
ZJ24F1114116	分析证书	Ab182803
ZJ24F1114115	分析证书	Ab182803
ZJ24F0607190	分析证书	Ab182803
ZJ24F0607189	分析证书	Ab182803
ZJ24F0607188	分析证书	Ab182803